Solem J O, Tengborn L, Steen S, Lührs C
Thorac Cardiovasc Surg. 1987 Feb;35(1):42-7. doi: 10.1055/s-2007-1020194.
Concentration of superfluous blood in the oxygenator after the termination of a cardiopulmonary bypass was studied in 46 aortocoronary bypass patients. 15 patients were treated with a centrifugation system, the Haemonetics Cell Saver, 16 patients were treated with the Gambro Hollow Fibre Hemofilter and the remaining 15 patients received as much as possible from the untreated oxygenator contents and served as controls in a coagulation study. Both methods functioned well, the time consumption for operation of the two systems was similar. The products differed greatly as centrifugation revealed highly concentrated red cells in saline solution while hemofiltration produced protein-rich concentrated whole blood. A coagulation study of the patients who had received the concentrated products showed no signs of activation of the coagulation factors nor of the fibrinolytic system.
对46例主动脉冠状动脉搭桥手术患者在体外循环结束后氧合器中多余血液的浓缩情况进行了研究。15例患者采用血液回收系统Haemonetics Cell Saver进行处理,16例患者采用Gambro中空纤维血液滤过器进行处理,其余15例患者尽可能多地接受未处理的氧合器内容物,并作为凝血研究的对照。两种方法均运行良好,两个系统的操作耗时相似。两种产品差异很大,因为离心法显示在盐溶液中有高度浓缩的红细胞,而血液滤过法产生富含蛋白质的浓缩全血。对接受浓缩产品的患者进行的凝血研究显示,没有凝血因子激活或纤维蛋白溶解系统激活的迹象。