Dariusz Szymanski, Adam Durczynski, Michal Nowicki, Janusz Strzelczyk, Department of General and Transplant Surgery, Barlicki University Hospital, Medical University of Lodz, 0-153 Lodz, Poland.
World J Gastroenterol. 2013 Dec 7;19(45):8321-5. doi: 10.3748/wjg.v19.i45.8321.
To evaluate the use of the Roux loop on the postoperative course in patients submitted for gastroenteroanastomosis (GE).
Non-jaundiced patients (n = 41) operated on in the Department of General and Transplant Surgery in Lodz, between January 2010 and December 2011 were enrolled. The tumor was considered unresectable when liver metastases or major vascular involvement were confirmed. Patients were randomized to receive Roux (n = 21) or conventional GE (n = 20) on a prophylactic basis.
The mean time to nasogastric tube withdrawal in Roux GE group was shorter (1.4 ± 0.75 vs 2.8 ± 1.1, P < 0.001). Time to starting oral liquids, soft diet and regular diet were decreased (2.3 ± 0.86 vs 3.45 ± 1.19; P < 0.001; 3.3 ± 0.73 vs 4.4 ± 1.23, P < 0.001 and 4.5 ± 0.76 vs 5.6 ± 1.42, P = 0.002; respectively). The Roux GE group had a lower use of prokinetics (10 mg thrice daily for 2.2 ± 1.8 d vs 3.7 ± 2.6 d, P = 0.044; total 62 ± 49 mg vs 111 ± 79 mg, P = 0.025). The mean hospitalization time following Roux GE was shorter (7.7 d vs 9.6 d, P = 0.006). Delayed gastric emptying (DGE) was confirmed in 20% after conventional GE but in none of the patients following Roux GE.
Roux gastrojejunostomy during open abdomen exploration in patients with unresectable pancreatic cancer is easy to perform, decreases the incidence of DGE and lowers hospitalization time.
评估 Roux 袢在接受胃肠吻合术(GE)的患者术后过程中的应用。
纳入 2010 年 1 月至 2011 年 12 月在 Lodz 普通外科和移植外科系接受手术的非黄疸患者(n=41)。当确认存在肝转移或主要血管受累时,肿瘤被认为不可切除。患者随机接受 Roux(n=21)或常规 GE(n=20)预防性治疗。
Roux GE 组拔鼻胃管时间更短(1.4±0.75 与 2.8±1.1,P<0.001)。开始口服液体、软食和常规饮食的时间也有所减少(2.3±0.86 与 3.45±1.19;P<0.001;3.3±0.73 与 4.4±1.23,P<0.001 和 4.5±0.76 与 5.6±1.42,P=0.002;分别)。Roux GE 组促动力药物的使用较少(10mg 每日 3 次,共 2.2±1.8 天与 3.7±2.6 天,P=0.044;总剂量 62±49mg 与 111±79mg,P=0.025)。Roux GE 组的平均住院时间较短(7.7 天与 9.6 天,P=0.006)。常规 GE 后有 20%的患者确认发生延迟性胃排空(DGE),但 Roux GE 后无一例发生。
在无法切除的胰腺癌患者开腹探查期间行 Roux 胃空肠吻合术操作简便,可降低 DGE 的发生率并缩短住院时间。