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腹腔镜下胰腺癌分期及手术治疗

Laparoscopic staging and surgical treatment of pancreatic cancer.

作者信息

Muniraj Thiruvengadam, Barve Pranav

机构信息

Section of Digestive Diseases, Yale University School of Medicine, CT, USA ; Department of Medicine, Griffin Hospital, CT, USA.

出版信息

N Am J Med Sci. 2013 Jan;5(1):1-9. doi: 10.4103/1947-2714.106183.

DOI:10.4103/1947-2714.106183
PMID:23378948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3560131/
Abstract

Pancreatic cancer is the tenth most common cancer and the fourth leading cause of cancer deaths in the United States. Surgery remains a cornerstone in the treatment of pancreatic cancer. Unfortunately, the percentage of patients presenting at the resectable stage is minimal. Although computed tomography (CT) scan remains the best modality to stage the tumor for resectability, laparoscopy and laparoscopic ultrasound offers its own advantages. Extended lymphadenectomy, portal vein resection, and arterial reconstruction have also been explored in multiple studies to enhance staging. The traditional pancreaticoduodenectomy (Whipple's procedure) with regional lymphadenectomy is still the standard of care in the surgical treatment of pancreatic cancer.

摘要

胰腺癌是美国第十大常见癌症,也是癌症死亡的第四大主要原因。手术仍然是胰腺癌治疗的基石。不幸的是,处于可切除阶段的患者比例极小。尽管计算机断层扫描(CT)仍是评估肿瘤可切除性分期的最佳方式,但腹腔镜检查和腹腔镜超声也有其自身优势。多项研究还探讨了扩大淋巴结清扫、门静脉切除和动脉重建以提高分期准确性。传统的胰十二指肠切除术(惠普尔手术)加区域淋巴结清扫仍是胰腺癌外科治疗的标准术式。

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本文引用的文献

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Cochrane Database Syst Rev. 2011 Feb 16(2):CD006053. doi: 10.1002/14651858.CD006053.pub3.
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CA Cancer J Clin. 2010 Sep-Oct;60(5):277-300. doi: 10.3322/caac.20073. Epub 2010 Jul 7.
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Vascular resection in pancreatic cancer surgery: survival determinants.胰腺癌手术中的血管切除:生存决定因素
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Survival after pancreatectomy with major arterial resection and reconstruction.胰腺切除联合主要动脉切除与重建后的生存情况。
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