Nisilevich V F, Pugacheva N L, Padiukov L N, Gruber I M, Reshilov L N
Zh Mikrobiol Epidemiol Immunobiol. 1987 Jan(1):8-12.
Nonencapsulated strains obtained by subculturing Streptococcus pneumoniae in a medium containing 0.5% of bile have been shown to possess a number of morphological and cultural features. The preparations obtained from the biomass of these strains by sonication have been found to possess antigenic, immunogenic and protective properties and to be specific to S. pneumoniae. The data obtained in this investigation may be considered indicative of the necessity for further study of these preparations with a view to their use for the analysis of serum samples taken from patients with bronchopulmonary diseases by means of enzyme immunoassay.
通过在含有0.5%胆汁的培养基中传代培养肺炎链球菌获得的非包膜菌株已显示出许多形态和培养特征。通过超声处理从这些菌株的生物质中获得的制剂已被发现具有抗原性、免疫原性和保护性,并且对肺炎链球菌具有特异性。本研究中获得的数据可被视为表明有必要进一步研究这些制剂,以便通过酶免疫测定法用于分析从支气管肺部疾病患者采集的血清样本。