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[晚期喉癌患者术后生存情况的回顾性分析]

[Retrospective analyses of postoperative survival of laryngeal carcinoma patients at late stage].

作者信息

Ma Yueying, Liu Liangfa, Huang Deliang, Wang Jialing, Wu Wenming, Liu Mingbo, Zhao Jiandong

机构信息

Department of Otolaryngology-Head and Neck Surgery, Chinese PLA General Hospital, Beijing, 100853, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Aug;27(15):844-6.

Abstract

OBJECTIVE

To compare the postoperative survival rate of laryngeal carcinoma patient at stage III or IV whom accepted partial laryngectomy and total laryngectomy.

METHOD

We performed a retrospective cohort follow-up study of 126 patients of stage III or IV who underwent operation for laryngeal carcinoma in Chinese PLA General Hospital between January, 2005 and December, 2009. Survival rates were calculated by product-limit method.

RESULT

There were 80 patients at stage III and 46 patient at stage IV. Sixty five patients underwent partial laryngectomy and 61 patients underwent total laryngectomy. There were 24 patients in whole group died in the 5 years, 15 of them underwent partial and 9 accepted total laryngectomy. The 5-years survival rate of partial and total group were 62.58% and 68.74% respectively. The survival curve of both groups had no significant difference (P < 0.05).

CONCLUSION

For laryngeal carcinoma patients at later stage, with suitable operative indication, the partial laryngectomy could achieve an acceptable effect as well as total laryngectomy.

摘要

目的

比较接受部分喉切除术和全喉切除术的Ⅲ期或Ⅳ期喉癌患者的术后生存率。

方法

对2005年1月至2009年12月在中国人民解放军总医院接受喉癌手术的126例Ⅲ期或Ⅳ期患者进行回顾性队列随访研究。生存率采用乘积极限法计算。

结果

Ⅲ期患者80例,Ⅳ期患者46例。65例行部分喉切除术,61例行全喉切除术。全组24例患者在5年内死亡,其中15例行部分喉切除术,9例行全喉切除术。部分喉切除组和全喉切除组的5年生存率分别为62.58%和68.74%。两组生存曲线差异无统计学意义(P<0.05)。

结论

对于晚期喉癌患者,在有合适手术指征的情况下,部分喉切除术与全喉切除术可取得相近的效果。

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