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右旋糖酐诱导的过敏反应中的代谢性酸中毒

Metabolic acidosis in dextran-induced anaphylactic reactions.

作者信息

Ljungström K G, Renck H

出版信息

Acta Anaesthesiol Scand. 1987 Feb;31(2):157-60. doi: 10.1111/j.1399-6576.1987.tb02540.x.

DOI:10.1111/j.1399-6576.1987.tb02540.x
PMID:2436431
Abstract

Results of arterial blood gas and acid-base balance analyses were analyzed in 50 patients suffering from dextran-induced anaphylactic reactions. Metabolic acidosis was always present in severe cases, leading to cardiac arrest, and also frequently found in those with less severe reactions with only slightly impaired circulation. Bronchospastic respiratory signs were frequently encountered but acidosis was noted to develop even without these symptoms. The severity of the acidosis was generally underestimated during treatment. Arterial PO2 and PCO2 were not significantly affected during these reactions.

摘要

对50例患有右旋糖酐诱导的过敏反应患者的动脉血气和酸碱平衡分析结果进行了分析。严重病例中始终存在代谢性酸中毒,可导致心脏骤停,在循环仅有轻微受损的不太严重反应的患者中也经常发现。支气管痉挛性呼吸体征经常出现,但即使没有这些症状也会出现酸中毒。治疗期间酸中毒的严重程度通常被低估。这些反应期间动脉血氧分压和二氧化碳分压没有受到显著影响。

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