IBD Centre, Division of Gastroenterology, Humanitas Clinical and Research Centre, Via Manzoni 56, 20089 Rozzano, Milan, Italy.
INSERM U954 and Department of Gastroenterology, Université de Lorraine, Vandoeuvre-lès-Nancy, France.
Nat Rev Gastroenterol Hepatol. 2014 Feb;11(2):84-6. doi: 10.1038/nrgastro.2013.246. Epub 2013 Dec 24.
In 2013, several new IBD drugs, including golimumab and vedolizumab, have been approved or completed successful programmes, showing efficacy in both Crohn’s disease and ulcerative colitis. In addition, classic IBD drugs have been formulated for colonic delivery, such as budesonide MMX®, which was recently approved for mild-to-moderate ulcerative colitis.
2013 年,包括戈利木单抗和维得利珠单抗在内的几种新型 IBD 药物已获得批准或完成了成功的项目,在克罗恩病和溃疡性结肠炎中均显示出疗效。此外,经典的 IBD 药物已被制成结肠递药系统,如布地奈德 MMX®,最近已被批准用于轻度至中度溃疡性结肠炎。