英国乳房筛查计划引入双视图乳房 X 光摄影后，间隔期癌症发病率降低。
Reduction in interval cancer rates following the introduction of two-view mammography in the UK breast screening programme.
机构信息
Policy Research Unit in Cancer Awareness, Screening and Early Diagnosis, Queen Mary, University of London, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK.
East Midlands Quality Assurance Reference Centre (QARC), Nottingham University Hospital City Campus, Hucknall Road, Nottingham NG5 1PB, UK.
出版信息
Br J Cancer. 2014 Feb 4;110(3):560-4. doi: 10.1038/bjc.2013.778. Epub 2013 Dec 24.
BACKGROUND
The introduction of two-view mammography at incident (subsequent) screens in the National Health Service Breast Screening Programme (NHSBSP) has led to an increased number of cancers detected at screen. However, the effect of two-view mammography on interval cancer rates has yet to be assessed.
METHODS
Routine screening and interval cancer data were collated from all screening programmes in the United Kingdom for women aged 50-64, screened between 1 April 2003 and 31 March 2005. Interval cancer rates were compared based on whether two-view mammography was in use at the last routine screen.
RESULTS
The reduction in interval cancers following screening using two-view mammography compared with one view was 0.68 per 1,000 women screened. Overall, this suggests the introduction of two-view mammography at incident screen was accompanied by a 15-20% reduction in interval cancer rates in the NHSBSP.
CONCLUSION
The introduction of two-view mammography at incident screens is associated with a reduction in incidence of interval cancers. This is consistent with previous publications on a contemporaneous increase in screen-detected cancers. The results provide further evidence of the benefit of the use of two-view mammography at incident screens.
背景
在国民保健服务乳房筛查计划（NHSBSP）中，在偶然（后续）筛查中引入双视图乳房 X 光检查，导致筛查中发现的癌症数量增加。然而，双视图乳房 X 光检查对间期癌症发生率的影响尚未得到评估。
方法
从英国所有筛查计划中收集了年龄在 50-64 岁的女性的常规筛查和间期癌症数据，筛查时间为 2003 年 4 月 1 日至 2005 年 3 月 31 日。根据最后一次常规筛查是否使用双视图乳房 X 光检查，比较间期癌症的发生率。
结果
与单视图相比，使用双视图乳房 X 光检查筛查后的间期癌症减少了 0.68/1000 名筛查女性。总体而言，这表明 NHSBSP 中引入双视图乳房 X 光检查在偶然筛查时，间期癌症的发生率降低了 15-20%。
结论
在偶然筛查中引入双视图乳房 X 光检查与间期癌症发生率的降低有关。这与之前关于同期筛查检出癌症增加的出版物一致。结果提供了进一步的证据，证明在偶然筛查中使用双视图乳房 X 光检查的益处。
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