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良性疾病子宫切除术后四年胎盘部位滋养细胞肿瘤非典型复发:病例报告及文献复习

Atypical recurrence of a placental site trophoblastic tumor four years after hysterectomy for benign condition: Case report and review of literature.

作者信息

Rauw L, Delbecque K, Goffin F, Golfier F, Georges P, Kridelka F

机构信息

Department of Pathology, University of Liège, Liège, Belgium.

Department of Obstetrics and Gynecology, University of Liège, Liège, Belgium ; Belgian Trophoblastic Disease Reference Center, University of Liège, Liège, Belgium.

出版信息

Gynecol Oncol Case Rep. 2013 May 31;6:36-8. doi: 10.1016/j.gynor.2013.05.006. eCollection 2013.

DOI:10.1016/j.gynor.2013.05.006
PMID:24371716
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3862214/
Abstract

•Rare case of PSTT limited to the vagina presenting eight years after last pregnancy and four years after hysterectomy•Differential diagnosis with other vaginal tumors can be challenging but it is critical because behavior and management are different.•Stage-adapted management is proposed and surgery is the mainstay treatment for localized disease.

摘要

•罕见病例:妊娠滋养细胞肿瘤局限于阴道,在末次妊娠8年后及子宫切除术后4年出现

•与其他阴道肿瘤进行鉴别诊断可能具有挑战性,但至关重要,因为其行为和治疗方法不同。

•建议采用根据分期的管理方法,手术是局限性疾病的主要治疗手段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a6/3862214/5d0a6aa6a4af/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a6/3862214/1012c79e9243/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a6/3862214/5d0a6aa6a4af/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a6/3862214/1012c79e9243/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a6/3862214/5d0a6aa6a4af/gr2.jpg

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本文引用的文献

1
Placental site trophoblastic tumours and the concept of fertility preservation.胎盘部位滋养细胞肿瘤与保留生育力的概念。
BJOG. 2012 Feb;119(3):369-74; discussion 374. doi: 10.1111/j.1471-0528.2011.03230.x. Epub 2011 Dec 13.
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Prognostic markers and long-term outcome of placental-site trophoblastic tumours: a retrospective observational study.胎盘部位滋养细胞肿瘤的预后标志物及长期结局:一项回顾性观察研究
Lancet. 2009 Jul 4;374(9683):48-55. doi: 10.1016/S0140-6736(09)60618-8. Epub 2009 Jun 22.
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Gestational trophoblastic diseases: 3. Human chorionic gonadotropin-free beta-subunit, a reliable marker of placental site trophoblastic tumors.
妊娠滋养细胞疾病:3. 人绒毛膜促性腺激素游离β亚基,胎盘部位滋养细胞肿瘤的可靠标志物。
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Placental site trophoblastic tumour: clinical features and management.胎盘部位滋养细胞肿瘤:临床特征与处理
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FIGO staging for gestational trophoblastic neoplasia 2000. FIGO Oncology Committee.2000年妊娠滋养细胞肿瘤的国际妇产科联盟(FIGO)分期。FIGO肿瘤学委员会。
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Placental site trophoblastic tumor: a 17-year experience at the New England Trophoblastic Disease Center.胎盘部位滋养细胞肿瘤:新英格兰滋养细胞疾病中心17年的经验
Gynecol Oncol. 2001 Sep;82(3):415-9. doi: 10.1006/gyno.2001.6265.
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Trophoblastic pseudotumor of the uterus: an exaggerated form of "syncytial endometritis" simulating a malignant tumor.子宫滋养细胞假瘤:一种模拟恶性肿瘤的“合体细胞性子宫内膜炎”的夸张形式。
Cancer. 1976 Sep;38(3):1214-26. doi: 10.1002/1097-0142(197609)38:3<1214::aid-cncr2820380323>3.0.co;2-j.