Raufman Jean-Pierre, Xu Su, Cheng Kunrong, Khurana Sandeep, Vivian Diana, Shi Da, Gullapalli Rao, Polli James
Division of Gastroenterology and Hepatology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Department of Diagnostic Radiology and Nuclear Medicine, School of Medicine, University of Maryland, Baltimore, Maryland, USA.
J Vet Sci Med Diagn. 2013 Mar 28;2(1). doi: 10.4172/2325-9590.1000110.
We used live-animal magnetic resonance imaging (MRI) to examine the gallbladders of male mice. These healthy mice were fasted overnight before the study and anesthetized in an animal chamber, with a gas mixture of oxygen and isoflurane for small animal MRI. In the course of these live-animal MRI studies, we observed a Phrygian cap appearance to the gallbladder of one healthy-appearing 6-week-old male mouse, similar to that of the human gallbladder described in many reports. After euthanasia for measurement of bile content, this mouse's gallbladder appeared anatomically normal. To our knowledge, this is the first report of a Phrygian cap appearance of the murine gallbladder.
我们使用活体动物磁共振成像(MRI)来检查雄性小鼠的胆囊。这些健康小鼠在研究前禁食过夜,并在动物舱中麻醉,使用氧气和异氟烷的混合气体进行小动物MRI检查。在这些活体动物MRI研究过程中,我们观察到一只看似健康的6周龄雄性小鼠的胆囊呈现出Phrygian帽样外观,类似于许多报告中描述的人类胆囊。在对该小鼠实施安乐死以测量胆汁含量后,其胆囊在解剖学上看起来正常。据我们所知,这是关于小鼠胆囊出现Phrygian帽样外观的首次报告。