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通过团体干预降低治疗阻力,可改善 2 型糖尿病患者的临床指标。

Reducing resistance to treatment, through group intervention, improves clinical measurements in patients with type 2 diabetes.

机构信息

Department of Clinical Quality, Meuhedet Health Care, 124 Ibn-Gvirol St, Tel Aviv, Israel.

出版信息

BMC Endocr Disord. 2013 Dec 28;13:61. doi: 10.1186/1472-6823-13-61.

Abstract

BACKGROUND

Studies have shown that group Therapeutic Patient Education (TPE) may empower patients with type 2 diabetes to better manage their disease. The mechanism of these interventions is not fully understood. A reduction in resistance to treatment may explain the mechanism by which TPE empowers participants to improve self-management. The Objective of this study was to examine the effectiveness of diabetes groups in reducing resistance to treatment and the association between reduced resistance and better management of the disease.

METHODS

In a program evaluation study, we administered validated questionnaires to measure resistance to treatment (RTQ) in 3 time periods: before the intervention (T1), immediately after the intervention (T2) and six months later (T3). Clinical measures (HbA1C, blood pressure, HDL, LDL and total cholesterol, Triglycerides and BMI) were retrieved from Maccabi Healthcare Services computerized systems, for T1;T2 and a year post intervention (T3). Linear mixed models were used adjusting for age, gender, social support and family status.

RESULTS

157; 156 and 106 TPE participants completed the RTQ in T1; T2 and T3 respectively. HbA1C and systolic and diastolic blood pressure were significantly reduced in the group which achieved a reduction in three out of the five RTQ components. For the other clinical measurements no significant changes were observed.

CONCLUSION

Our findings suggest that reducing resistance to treatment, through an educational program for patients with diabetes, is associated with a better disease control. Identifying patients with higher resistance to treatment, and including components that reduce resistance in patient education programs, have the potential to increase the effectiveness of these programs.

摘要

背景

研究表明,团体治疗性患者教育(TPE)可能使 2 型糖尿病患者能够更好地管理自己的疾病。这些干预措施的机制尚不完全清楚。治疗抵抗的降低可能解释了 TPE 使参与者能够改善自我管理的机制。本研究的目的是检验糖尿病小组在降低治疗抵抗方面的有效性,以及降低抵抗与更好地管理疾病之间的关联。

方法

在一项方案评估研究中,我们使用经过验证的问卷在 3 个时间点测量治疗抵抗(RTQ):干预前(T1)、干预后立即(T2)和 6 个月后(T3)。临床指标(HbA1C、血压、HDL、LDL 和总胆固醇、甘油三酯和 BMI)从 Maccabi 医疗保健服务的计算机系统中检索,用于 T1;T2 和干预后 1 年(T3)。使用线性混合模型进行调整,以适应年龄、性别、社会支持和家庭状况。

结果

157;156 和 106 名 TPE 参与者分别在 T1、T2 和 T3 完成了 RTQ。HbA1C 以及收缩压和舒张压在 5 个 RTQ 成分中有 3 个降低的组中显著降低。对于其他临床测量,没有观察到显著变化。

结论

我们的研究结果表明,通过针对糖尿病患者的教育计划降低治疗抵抗与更好的疾病控制相关。通过识别具有更高治疗抵抗的患者,并在患者教育计划中纳入降低抵抗的成分,有可能提高这些计划的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0e1/3909345/f929380c25d0/1472-6823-13-61-1.jpg

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