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2006-2010 年美国体外受精多胎妊娠中单卵双胎的影响。

Impact of monozygotic twinning on multiple births resulting from in vitro fertilization in the United States, 2006-2010.

机构信息

Louisiana State University Department of Obstetrics and Gynecology, and School of Public Health, New Orleans, LA; Louisiana State University School of Medicine, and School of Public Health, New Orleans, LA.

Louisiana State University Department of Obstetrics and Gynecology, and School of Public Health, New Orleans, LA; The Fertility Institute of New Orleans, Mandeville, LA.

出版信息

Am J Obstet Gynecol. 2014 May;210(5):468.e1-6. doi: 10.1016/j.ajog.2013.12.034. Epub 2013 Dec 25.

Abstract

OBJECTIVE

To determine the contribution of monozygotic twining to in vitro fertilization multiple births.

STUDY DESIGN

We performed a retrospective analysis of the incidence of monozygotic twining in multiple births resulting from fresh embryo transfers using 2006-2010 data from the Society for Reproductive Technology Clinic Outcome Reporting System.

RESULTS

The number of embryos transferred were fewer than the number of births in 0.5% (223/40950) of twin, 29% (659/2289) of triplet, and 64% (43/67) of quadruplet births resulting from transfer of fresh embryos from 2006 to 2010. In 2010, 37% of triplets and 100% of quadruplet births occurred when fewer than 3 and fewer than 4 embryos respectively were transferred.

CONCLUSION

Monozygotic twinning plays a key role in the development of triplet and quadruplet pregnancies achieved through in vitro fertilization.

摘要

目的

确定同卵双胞胎妊娠对体外受精多胎妊娠的贡献。

研究设计

我们对 2006 年至 2010 年生殖技术学会临床结果报告系统的数据进行了回顾性分析,以确定新鲜胚胎移植后多胎妊娠中同卵双胞胎妊娠的发生率。

结果

在 2006 年至 2010 年期间,从新鲜胚胎移植中产生的双胞胎、三胞胎和四胞胎的出生数量中,有 0.5%(223/40950)的双胞胎、29%(659/2289)的三胞胎和 64%(43/67)的四胞胎的转移胚胎数量少于出生数量。在 2010 年,当转移的胚胎数量分别少于 3 个和 4 个时,37%的三胞胎和 100%的四胞胎妊娠发生。

结论

同卵双胞胎妊娠在体外受精导致的三胞胎和四胞胎妊娠的发展中起着关键作用。

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