Dolomisiewicz Edward A, Miller Matthew E, Potter Benjamin K
Department of Physical Medicine and Rehabilitation, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20889(∗).
Department of Physical Medicine and Rehabilitation, Walter Reed National Military Medical Center, Bethesda, MD(†).
PM R. 2014 Mar;6(3):279-83. doi: 10.1016/j.pmrj.2013.10.004. Epub 2013 Dec 24.
Heterotopic ossification (HO) is the process of abnormal formation of lamellar bone in nonosseous tissues. In this case presentation, we describe patients with aggressive HO, which becomes symptomatic shortly after injury for which we have suggested the term "fulminant heterotopic ossification." These atypical presentations of fulminant HO highlight the necessity for continued research directed at improved understanding of HO and may suggest a role for early partial surgical excision as a definitive management strategy.
异位骨化（HO）是指在非骨组织中异常形成板层骨的过程。在本病例报告中，我们描述了患有侵袭性HO的患者，其在受伤后不久即出现症状，对此我们建议使用“暴发性异位骨化”这一术语。暴发性HO的这些非典型表现凸显了持续开展研究以更好地理解HO的必要性，并且可能提示早期部分手术切除作为一种确定性治疗策略的作用。
