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Propranolol: a novel antihemangioma agent with multiple potential mechanisms of action.

作者信息

Ji Yi, Chen Siyuan, Li Kai, Xiao Xianmin, Zheng Shan

机构信息

Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai, China, Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China Research Institute of Pediatrics, Children's Hospital of Fudan University, Shanghai, China Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai, China

出版信息

Ann Surg. 2015 Feb;261(2):e52-3. doi: 10.1097/SLA.0000000000000450.

DOI:10.1097/SLA.0000000000000450
PMID:24374526
Abstract
摘要

相似文献

1
Propranolol: a novel antihemangioma agent with multiple potential mechanisms of action.普萘洛尔:一种具有多种潜在作用机制的新型抗血管瘤药物。
Ann Surg. 2015 Feb;261(2):e52-3. doi: 10.1097/SLA.0000000000000450.
2
Reply to letter: "propranolol: a novel antihemangioma agent with multiple potential mechanisms of action".致信回复:“普萘洛尔:一种具有多种潜在作用机制的新型抗血管瘤药物”
Ann Surg. 2015 Feb;261(2):e53. doi: 10.1097/SLA.0000000000000453.
3
Propranolol induces regression of hemangioma cells through HIF-1α-mediated inhibition of VEGF-A.普萘洛尔通过 HIF-1α 介导的 VEGF-A 抑制诱导血管细胞瘤细胞消退。
Ann Surg. 2012 Jul;256(1):146-56. doi: 10.1097/SLA.0b013e318254ce7a.
4
Propranolol accelerates adipogenesis in hemangioma stem cells and causes apoptosis of hemangioma endothelial cells.普萘洛尔加速血管瘤干细胞脂肪生成并引起血管瘤内皮细胞凋亡。
Plast Reconstr Surg. 2012 Nov;130(5):1012-1021. doi: 10.1097/PRS.0b013e318267d3db.
5
Propranolol inhibits the proliferation, migration and tube formation of hemangioma cells through HIF-1α dependent mechanisms.普萘洛尔通过依赖缺氧诱导因子-1α(HIF-1α)的机制抑制血管瘤细胞的增殖、迁移和管腔形成。
Braz J Med Biol Res. 2017 Oct 2;50(12):e6138. doi: 10.1590/1414-431X20176138.
6
Propranolol targets the contractility of infantile haemangioma-derived pericytes.普萘洛尔作用于婴儿血管瘤来源的周细胞的收缩性。
Br J Dermatol. 2014 Nov;171(5):1129-37. doi: 10.1111/bjd.13048. Epub 2014 Aug 28.
7
Propranolol induces regression of hemangioma cells via the down-regulation of the PI3K/Akt/eNOS/VEGF pathway.普萘洛尔通过下调PI3K/Akt/eNOS/VEGF通路诱导血管瘤细胞消退。
Pediatr Blood Cancer. 2015 Aug;62(8):1414-20. doi: 10.1002/pbc.25453. Epub 2015 Mar 1.
8
Serum-level changes of vascular endothelial growth factor in children with infantile hemangioma after oral propranolol therapy.口服普萘洛尔治疗后婴幼儿血管瘤患儿血清血管内皮生长因子水平的变化
Pediatr Dermatol. 2013 Sep-Oct;30(5):549-53. doi: 10.1111/pde.12192. Epub 2013 Aug 5.
9
Upregulated autocrine vascular endothelial growth factor (VEGF)/VEGF receptor-2 loop prevents apoptosis in haemangioma-derived endothelial cells.上调的自分泌血管内皮生长因子 (VEGF)/VEGF 受体-2 环可防止血管瘤衍生的内皮细胞凋亡。
Br J Dermatol. 2014 Jan;170(1):78-86. doi: 10.1111/bjd.12592.
10
Propranolol represses infantile hemangioma cell growth through the β2-adrenergic receptor in a HIF-1α-dependent manner.普萘洛尔通过β2-肾上腺素能受体以低氧诱导因子-1α(HIF-1α)依赖的方式抑制婴儿血管瘤细胞生长。
Oncol Rep. 2015 Jun;33(6):3099-107. doi: 10.3892/or.2015.3911. Epub 2015 Apr 14.

引用本文的文献

1
Intolerable side effects during propranolol therapy for infantile hemangioma: frequency, risk factors and management.婴儿血管瘤普萘洛尔治疗期间无法耐受的副作用:频率、危险因素和管理。
Sci Rep. 2018 Mar 9;8(1):4264. doi: 10.1038/s41598-018-22787-8.
2
Signaling pathways in the development of infantile hemangioma.婴儿血管瘤发育中的信号通路。
J Hematol Oncol. 2014 Jan 31;7:13. doi: 10.1186/1756-8722-7-13.