采用单光子发射计算机断层扫描评估电针对儿童自闭症的治疗效果。
Evaluating the effectiveness of electro-acupuncture as a treatment for childhood autism using single photon emission computed tomography.
机构信息
Department of Nuclear Medicine, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, 518036, China.
出版信息
Chin J Integr Med. 2014 Jan;20(1):19-23. doi: 10.1007/s11655-014-1680-2. Epub 2013 Dec 29.
OBJECTIVE
To explore the effectiveness of electro-acupuncture (EA) in the treatment of childhood autism (CA) and evaluate its effectiveness using single photon emission computed tomography (SPECT).
METHODS
A total of 55 CA patients (4.52±2.73 years) were enrolled in this study. All patients received EA treatments and were examined by SPECT before and after treatments.
RESULTS
Following treatment, the intracerebral multiple focal radioactivity distribution defect areas of CA patients were observed to be partially filled. Specifically, significant differences in the ratios of regional cerebral blood flow and global cerebral blood flow before (Fb) and after (Fe) EA treatment in different lesions were observed (in the left prefrontal cortex, t=5.01, P<0.01; in the right prefrontal cortex, t=2.32, P<0.05; in the left temporal lobe, t=4.54, P<0.01; in the right temporal lobe, t=2.90, P<0.05; in the left Broca's area, t=5.82, P<0.01). After EA treatment, the patients exhibited symptomatic relief.
CONCLUSION
EA is useful to treat CA and SPECT can be used to evaluate the effectiveness of this treatment.
目的
探索电针对儿童自闭症（CA）的治疗效果，并使用单光子发射计算机断层扫描（SPECT）评估其疗效。
方法
共纳入 55 例 CA 患者（4.52±2.73 岁）。所有患者均接受电针治疗，并在治疗前后进行 SPECT 检查。
结果
治疗后，CA 患者颅内多个局灶放射性分布缺损区部分填充。具体来说，不同病灶的局部脑血流和全脑血流治疗前后比值（Fe/Fb）差异有统计学意义（左前额叶 t=5.01，P<0.01；右前额叶 t=2.32，P<0.05；左颞叶 t=4.54，P<0.01；右颞叶 t=2.90，P<0.05；左布罗卡区 t=5.82，P<0.01）。电针治疗后，患者症状缓解。
结论
电针治疗 CA 有效，SPECT 可用于评估该治疗方法的疗效。
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