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在句法理解测试中对正常受试者和失语症受试者的区分。

Discrimination of normal and aphasic subjects on a test of syntactic comprehension.

作者信息

Caplan D

出版信息

Neuropsychologia. 1987;25(1B):173-84. doi: 10.1016/0028-3932(87)90129-1.

DOI:10.1016/0028-3932(87)90129-1
PMID:2437492
Abstract

An Anglophone population consisting of 37 aphasic patients and 23 normal control subjects, and a Francophone population consisting of 49 aphasic patients and 23 control subjects were given a task requiring the comprehension of syntactic structures for the correct assignment of thematic roles to nouns. Discriminant analysis was used to classify subjects into aphasic and normal groups according to their scores on the task. In both populations--Anglophone and Francophone--most of the subjects were classified into their actual groups except for an occasional normal subject classified with the aphasic group and a small number of aphasics classified as normal. A cut-off score below which performance is clearly abnormal and above which performance is clearly normal can be set for this test. Patients who performed normally on this test had lesions affecting any single lobe within the dominant perisylvian cortex and mostly consisted of patients with dysarthria, apraxia of speech, and 'mixed' aphasia types. The results have implications for the incidence of aphasic disturbances of syntactic comprehension and for the nature of language representation in the brain.

摘要

对由37名失语症患者和23名正常对照受试者组成的英语人群,以及由49名失语症患者和23名对照受试者组成的法语人群,进行了一项任务,该任务要求理解句法结构以便将题元角色正确分配给名词。判别分析用于根据受试者在该任务上的得分将其分为失语症组和正常组。在英语和法语这两个人群中,除了偶尔有正常受试者被归入失语症组以及少数失语症患者被归类为正常外,大多数受试者都被归入了他们实际所属的组。可以为该测试设定一个临界分数,低于该分数表现明显异常,高于该分数表现明显正常。在该测试中表现正常的患者,其病变影响优势侧颞叶周围皮质内的任何一个单一脑叶,且大多为构音障碍、言语失用症和“混合性”失语症类型的患者。这些结果对句法理解失语症障碍的发生率以及大脑中语言表征的性质具有启示意义。

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