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妊娠期严重生物瓣二尖瓣狭窄

Severe bioprosthetic mitral valve stenosis in pregnancy.

作者信息

Munoz-Mendoza Jerson, Pinto Miranda Veronica, Tanawuttiwat Tanyanan, Badiye Amit, Chaparro Sandra V

机构信息

Department of Medicine, University of Miami/Jackson Memorial Hospital, 1611 NW 12th Avenue, Central Building, Room 600D, Miami, FL, 33136, USA.

Division of Cardiology, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.

出版信息

Gen Thorac Cardiovasc Surg. 2016 Jan;64(1):38-42. doi: 10.1007/s11748-013-0366-6. Epub 2013 Dec 29.

Abstract

A 21-year-old woman in the 16th week of pregnancy was admitted due to acute presentation of severe exertional dyspnea. She had undergone mitral valve replacement (MVR) with bioprosthetic valve for infective endocarditis 2 years ago. She developed congestive heart failure from mitral bioprosthetic valve stenosis due to early structural valve deterioration. She also had severe pulmonary hypertension and underwent a redo MVR using a mechanical valve prosthesis with good maternal outcome but fetal demise. This report brings up the debate about what type of valve should be used in women in reproductive age, and discusses the management of severe mitral stenosis and stenosis of a bioprosthetic valve during pregnancy. Surgical options can almost always be delayed until fetal maturity is achieved and a simultaneous cesarean section can be performed. However, under certain circumstances when the maternal welfare is in jeopardy the surgical intervention is mandatory even before the fetus reaches viability.

摘要

一名怀孕16周的21岁女性因严重劳力性呼吸困难急性发作入院。她两年前因感染性心内膜炎接受了生物瓣膜二尖瓣置换术(MVR)。由于早期人工瓣膜结构退化,她因生物二尖瓣狭窄发展为充血性心力衰竭。她还患有严重的肺动脉高压,并接受了再次MVR,使用了机械瓣膜假体,产妇结局良好,但胎儿死亡。本报告引发了关于育龄女性应使用何种类型瓣膜的争论,并讨论了妊娠期间严重二尖瓣狭窄和生物瓣膜狭窄的管理。手术选择几乎总是可以推迟到胎儿成熟,同时进行剖宫产。然而,在某些情况下,当产妇的健康受到威胁时,即使胎儿尚未达到存活能力,手术干预也是必要的。

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