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容积调强弧形治疗中使用射野剂量测定法进行出射剂量分析。

Exit fluence analysis using portal dosimetry in volumetric modulated arc therapy.

作者信息

Sukumar Prabakar, Padmanaban Sriram, Rajasekaran Dhanabalan, Kannan Muniyappan, Nagarajan Vivekanandan

机构信息

Medical Physics Department, Cancer Institute (WIA), India.

Anna University, India.

出版信息

Rep Pract Oncol Radiother. 2012 Jul 15;17(6):324-31. doi: 10.1016/j.rpor.2012.06.003. eCollection 2012.

Abstract

AIM

In measuring exit fluences, there are several sources of deviations which include the changes in the entrance fluence, changes in the detector response and patient orientation or geometry. The purpose of this work is to quantify these sources of errors.

BACKGROUND

The use of the volumetric modulated arc therapy treatment with the help of image guidance in radiotherapy results in high accuracy of delivering complex dose distributions while sparing critical organs. The transit dosimetry has the potential of Verifying dose delivery by the linac, Multileaf collimator positional accuracy and the calculation of dose to a patient or phantom.

MATERIALS AND METHODS

The quantification of errors caused by a machine delivery is done by comparing static and arc picket fence test for 30 days. A RapidArc plan, created for the pelvis site was delivered without and with Rando phantom and exit portal images were acquired. The day to day dose variation were analysed by comparing the daily exit dose images during the course of treatment. The gamma criterion used for analysis is 3% dose difference and 3 mm distance to agreement with a threshold of 10% of maximum dose.

RESULTS

The maximum standard deviation for the static and arc picket fence test fields were 0.19 CU and 1.3 CU, respectively. The delivery of the RapidArc plans without a phantom shows the maximum standard deviation of 1.85 CU and the maximum gamma value of 0.59. The maximum gamma value for the RapidArc plan delivered with the phantom was found to be 1.2. The largest observed fluence deviation during the delivery to patient was 5.7% and the maximum standard deviation was 4.1 CU.

CONCLUSION

It is found from this study that the variation due to patient anatomy and interfraction organ motion is significant.

摘要

目的

在测量出射注量时,存在多种偏差来源,包括入射注量的变化、探测器响应的变化以及患者的体位或几何形状变化。本研究的目的是对这些误差来源进行量化。

背景

在放射治疗中借助图像引导使用容积调强弧形治疗可在保护关键器官的同时高精度地输送复杂的剂量分布。传输剂量测定法有潜力验证直线加速器的剂量输送、多叶准直器的位置精度以及患者或体模的剂量计算。

材料与方法

通过比较30天的静态和弧形栅栏测试来量化机器输送引起的误差。针对骨盆部位创建的快速弧形计划在不使用和使用朗多体模的情况下进行输送,并采集出射门静脉图像。通过比较治疗过程中的每日出射剂量图像来分析每日剂量变化。用于分析的伽马标准是3%的剂量差异和3毫米的距离一致性,阈值为最大剂量的10%。

结果

静态和弧形栅栏测试野的最大标准偏差分别为0.19 CU和1.3 CU。不使用体模输送快速弧形计划时,最大标准偏差为1.85 CU,最大伽马值为0.59。使用体模输送快速弧形计划时,发现最大伽马值为1.2。在向患者输送过程中观察到的最大注量偏差为5.7%,最大标准偏差为4.1 CU。

结论

本研究发现,由于患者解剖结构和分次间器官运动导致的变化是显著的。

相似文献

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Comparison of sources of exit fluence variation for IMRT.比较调强放疗中外照射量变化的来源。
Phys Med Biol. 2009 Oct 7;54(19):N451-8. doi: 10.1088/0031-9155/54/19/N03. Epub 2009 Sep 4.

本文引用的文献

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Comparison of sources of exit fluence variation for IMRT.比较调强放疗中外照射量变化的来源。
Phys Med Biol. 2009 Oct 7;54(19):N451-8. doi: 10.1088/0031-9155/54/19/N03. Epub 2009 Sep 4.

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