Department of Experimental Psychology, Oxford University, 9 South Parks Road, Oxford OX1 3UD, UK.
Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham, Birmingham B15 2 TT, UK.
Neuropsychologia. 2014 Feb;54:11-7. doi: 10.1016/j.neuropsychologia.2013.12.016. Epub 2013 Dec 27.
We examined the frequency and severity of visual versus tactile extinction based on data from a large group of sub-acute patients (n=454) with strokes affecting different vascular territories. After right hemisphere damage visual and tactile extinction were equally common. However, after left hemisphere damage tactile extinction was more common than visual. The frequency of extinction was significantly higher in patients with right compared to left hemisphere damage in both visual and tactile modalities but this held only for strokes affecting the MCA and PCA territories and not for strokes affecting other vascular territories. Furthermore, the severity of extinction did not differ as a function of either the stimulus modality (visual versus tactile), the affected hemisphere (left versus right) or the stroke territory (MCA, PCA or other vascular territories). We conclude that the frequency but not severity of extinction in both modalities relates to the side of damage (i.e. left versus right hemisphere) and the vascular territories affected by the stroke, and that left hemisphere dominance for motor control may link to the greater incidence of tactile than visual extinction after left hemisphere stroke. We discuss the implications of our findings for understanding hemispheric lateralization within visuospatial attention networks.
我们根据一组影响不同血管区域的亚急性患者（n=454）的大量数据，研究了视觉与触觉失认的频率和严重程度。右半球损伤后，视觉和触觉失认同样常见。然而，左半球损伤后，触觉失认比视觉失认更常见。在视觉和触觉两种模式下，右半球损伤患者的失认频率明显高于左半球损伤患者，但这种情况仅适用于影响 MCA 和 PCA 区域的中风，而不适用于影响其他血管区域的中风。此外，失认的严重程度与刺激模式（视觉与触觉）、受影响的半球（左与右）或中风区域（MCA、PCA 或其他血管区域）无关。我们得出结论，两种模式下失认的频率而非严重程度与损伤侧（即左半球与右半球）和中风影响的血管区域有关，而左半球对运动控制的优势可能与左半球中风后触觉失认比视觉失认更为常见有关。我们讨论了我们的发现对理解视觉空间注意网络中半球偏侧化的意义。
