缺血修饰白蛋白可预测嵌顿疝的坏死。
Ischemia modified albumin can predict necrosis at incarcerated hernias.
机构信息
General Surgery Department, Medical Faculty, Bezmialem Vakıf University Hospital, Adnan Menderes Bulvarı Vatan Caddesi, 34093 Fatih, İstanbul, Turkey.
Anesthesiology Department, Medical Faculty, Dokuz Eylül University, İzmir, Turkey.
出版信息
Dis Markers. 2013;35(6):807-10. doi: 10.1155/2013/185425. Epub 2013 Nov 27.
Abstract
PURPOSE
To evaluate the predictive effect of IMA in incarcerated hernias.
METHODS
Three groups (n = 7) of rats were operated. Group I aimed to mimic incarceration, group II aimed the strangulation, and group III was the sham group. IMA and LDH measurements were made.
RESULTS
IMA levels were significantly higher in strangulation mimicking group and IMA levels were normal at postoperative 6th hour in incarceration mimicking group. LDH levels were significantly higher in both incarceration and strangulation mimicking groups.
CONCLUSION
IMA seems to be an effective marker in incarcerated hernias to predict necrosis. But we need further studies to generalise this hypothesis.
摘要
目的
评估 IMA 在嵌顿疝中的预测效果。
方法
对三组（每组 n = 7）大鼠进行手术。第 I 组旨在模拟嵌顿，第 II 组旨在模拟绞窄，第 III 组为假手术组。测量 IMA 和 LDH 水平。
结果
在模拟绞窄的组中，IMA 水平显著升高，而在模拟嵌顿的组中，IMA 水平在术后 6 小时正常。在嵌顿和绞窄模拟组中，LDH 水平均显著升高。
结论
IMA 似乎是一种预测嵌顿疝组织坏死的有效标志物。但我们需要进一步的研究来推广这一假设。
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