Agarwal Krishan Kant, Karunanithi Sellam, Jain Sachin, Kumar Rakesh
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Indian J Nucl Med. 2013 Oct;28(4):237-9. doi: 10.4103/0972-3919.121973.
Hypercalcemia is associated with gynecologic malignant diseases, and cases involving various organs such as the uterus, ovaries, vulva, and vagina. This may be due to elevated levels of parathyroid hormone-related peptide (PTHrP). We describe here two cases of ovarian carcinoma simultaneously producing PTHrP that caused hypercalcemia and metastatic calcification detected on 18F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography-computed tomography (PET-CT).
高钙血症与妇科恶性疾病相关,且病例涉及子宫、卵巢、外阴和阴道等多个器官。这可能是由于甲状旁腺激素相关肽(PTHrP)水平升高所致。我们在此描述两例卵巢癌同时产生PTHrP导致高钙血症及在18F-氟脱氧葡萄糖(18F-FDG)正电子发射断层扫描-计算机断层扫描(PET-CT)上检测到转移性钙化的病例。