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卵巢癌分泌甲状旁腺激素相关蛋白导致高钙血症及(18)F-FDG PET-CT检测到转移性钙化。

Ovarian carcinoma producing parathyroid hormone-related protein causing hypercalcemia and metastatic calcification detected on (18)F-FDG PET-CT.

作者信息

Agarwal Krishan Kant, Karunanithi Sellam, Jain Sachin, Kumar Rakesh

机构信息

Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Nucl Med. 2013 Oct;28(4):237-9. doi: 10.4103/0972-3919.121973.

Abstract

Hypercalcemia is associated with gynecologic malignant diseases, and cases involving various organs such as the uterus, ovaries, vulva, and vagina. This may be due to elevated levels of parathyroid hormone-related peptide (PTHrP). We describe here two cases of ovarian carcinoma simultaneously producing PTHrP that caused hypercalcemia and metastatic calcification detected on 18F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography-computed tomography (PET-CT).

摘要

高钙血症与妇科恶性疾病相关,且病例涉及子宫、卵巢、外阴和阴道等多个器官。这可能是由于甲状旁腺激素相关肽(PTHrP)水平升高所致。我们在此描述两例卵巢癌同时产生PTHrP导致高钙血症及在18F-氟脱氧葡萄糖(18F-FDG)正电子发射断层扫描-计算机断层扫描(PET-CT)上检测到转移性钙化的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3baa/3866672/dffd25a48c55/IJNM-28-237-g001.jpg

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