癌症恶病质中疾病特异性底物——现状与展望。
Disease specific substrates in cancer cachexia - Reality and anticipation.
作者信息
Zadák Zdeněk, Tichá Alena, Hyšpler Radomír
机构信息
Department of Research and Development, University Hospital and Faculty of Medicine, Hradec Králové, Czech Republic.
出版信息
Rep Pract Oncol Radiother. 2012 Dec 5;18(1):34-43. doi: 10.1016/j.rpor.2012.10.008.
Abstract
In recent years, the concept of nutrition in patients with tumour diseases has been changing very significantly. The article discusses the pathogenesis of tumour cachexia and sarcopenia, which have been intensively studied, particularly in the last ten years. The possibilities and modern approaches in nutritional support in oncology are reviewed with a special emphasis on the group of elderly patients. Also, a detailed list of the most frequently used pharmaconutrients in oncology is presented. The recommendations for nutritional care of elderly oncological patients are given and discussed.
摘要
近年来，肿瘤疾病患者的营养观念发生了非常显著的变化。本文讨论了肿瘤恶病质和肌肉减少症的发病机制，尤其是在过去十年中对其进行了深入研究。本文回顾了肿瘤学营养支持的可能性和现代方法，并特别强调了老年患者群体。此外，还列出了肿瘤学中最常用的营养药物的详细清单。给出并讨论了老年肿瘤患者营养护理的建议。
相似文献
1
Disease specific substrates in cancer cachexia - Reality and anticipation.
Rep Pract Oncol Radiother. 2012 Dec 5;18(1):34-43. doi: 10.1016/j.rpor.2012.10.008.
2
Computed tomography diagnosed cachexia and sarcopenia in 725 oncology patients: is nutritional screening capturing hidden malnutrition?
J Cachexia Sarcopenia Muscle. 2018 Apr;9(2):295-305. doi: 10.1002/jcsm.12258. Epub 2017 Dec 21.
3
Sarcopenia, Malnutrition, and Cachexia: Adapting Definitions and Terminology of Nutritional Disorders in Older People with Cancer.
Nutrients. 2021 Feb 26;13(3):761. doi: 10.3390/nu13030761.
4
Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) "cachexia-anorexia in chronic wasting diseases" and "nutrition in geriatrics".
Clin Nutr. 2010 Apr;29(2):154-9. doi: 10.1016/j.clnu.2009.12.004. Epub 2010 Jan 8.
5
Cancer-associated malnutrition, cachexia and sarcopenia: the skeleton in the hospital closet 40 years later.
Proc Nutr Soc. 2016 May;75(2):199-211. doi: 10.1017/S002966511500419X. Epub 2016 Jan 20.
6
Cachexia versus sarcopenia.
Curr Opin Clin Nutr Metab Care. 2011 Jan;14(1):15-21. doi: 10.1097/MCO.0b013e328340c2c2.
7
Sarcopenia and cachexia in the era of obesity: clinical and nutritional impact.
Proc Nutr Soc. 2016 May;75(2):188-98. doi: 10.1017/S0029665115004279. Epub 2016 Jan 8.
8
Impact of Sarcopenia as a Prognostic Biomarker of Bladder Cancer.
Int J Mol Sci. 2018 Oct 1;19(10):2999. doi: 10.3390/ijms19102999.
9
Impact of a multidisciplinary rehabilitation nutrition team on evaluating sarcopenia, cachexia and practice of rehabilitation nutrition.
J Med Invest. 2017;64(1.2):140-145. doi: 10.2152/jmi.64.140.
10
Nutrition Support for Persistent Inflammation, Immunosuppression, and Catabolism Syndrome.
Nutr Clin Pract. 2017 Apr;32(1_suppl):121S-127S. doi: 10.1177/0884533616687502. Epub 2017 Feb 6.
引用本文的文献
1
Malnutrition and cachexia in patients with head and neck cancer treated with (chemo)radiotherapy.
Rep Pract Oncol Radiother. 2015 Jul-Aug;20(4):249-58. doi: 10.1016/j.rpor.2015.03.001. Epub 2015 Mar 29.
2
Cancer in the elderly.
Rep Pract Oncol Radiother. 2012 Dec 23;18(1):1-5. doi: 10.1016/j.rpor.2012.11.001. eCollection 2012.
本文引用的文献
1
Assessment of health status in elderly patients with cancer.
Rep Pract Oncol Radiother. 2012 Aug 9;18(1):44-8. doi: 10.1016/j.rpor.2012.07.007. eCollection 2012.
2
Breast cancer in the elderly-Should it be treated differently?
Rep Pract Oncol Radiother. 2012 Jul 15;18(1):26-33. doi: 10.1016/j.rpor.2012.05.005.
3
Regulation of inflammation in cancer by eicosanoids.
Prostaglandins Other Lipid Mediat. 2011 Nov;96(1-4):27-36. doi: 10.1016/j.prostaglandins.2011.08.004. Epub 2011 Aug 16.
4
Beyond anorexia -cachexia. Nutrition and modulation of cancer patients' metabolism: supplementary, complementary or alternative anti-neoplastic therapy?
Eur J Pharmacol. 2011 Sep;668 Suppl 1:S87-90. doi: 10.1016/j.ejphar.2011.06.060. Epub 2011 Jul 27.
5
Stimulation of the nicotine antiinflammatory pathway improves food intake and body composition in tumor-bearing rats.
Nutr Cancer. 2011;63(2):295-9. doi: 10.1080/01635581.2011.530736.
6
Definition and classification of cancer cachexia: an international consensus.
Lancet Oncol. 2011 May;12(5):489-95. doi: 10.1016/S1470-2045(10)70218-7. Epub 2011 Feb 4.
7
Heart rate variability and length of survival in hospice cancer patients.
J Korean Med Sci. 2010 Aug;25(8):1140-5. doi: 10.3346/jkms.2010.25.8.1140. Epub 2010 Jul 21.
8
Prevalence, risk factors and clinical implications of malnutrition in French Comprehensive Cancer Centres.
Br J Cancer. 2010 Mar 16;102(6):966-71. doi: 10.1038/sj.bjc.6605578. Epub 2010 Feb 16.
9
The association between autonomic dysfunction and survival in male patients with advanced cancer: a preliminary report.
J Pain Symptom Manage. 2010 Feb;39(2):283-90. doi: 10.1016/j.jpainsymman.2009.06.014.
10
Early nutritional intervention improves treatment tolerance and outcomes in head and neck cancer patients undergoing concurrent chemoradiotherapy.
Support Care Cancer. 2010 Jul;18(7):837-45. doi: 10.1007/s00520-009-0717-0. Epub 2009 Aug 30.
Zotero 插件