Suppr超能文献

再次主动脉瓣置换术:无缝合技术

REDO aortic valve replacement: the sutureless approach.

作者信息

Santarpino Giuseppe, Pfeiffer Steffen, Concistrè Giovanni, Fischlein Theodor

机构信息

Department of Cardiac Surgery, Klinikum Nürnberg, Nuremberg, Germany.

出版信息

J Heart Valve Dis. 2013 Sep;22(5):615-20.

Abstract

BACKGROUND AND AIM OF THE STUDY

The study aim was to report the results of a single-center cohort of patients who underwent aortic valve replacement (AVR) with a sutureless prosthesis in case of cardiac reoperation (REDO).

METHODS

Between March 2010 and December 2011, a total of 83 patients underwent AVR with the Perceval S sutureless aortic bioprosthesis (Sorin Biomedica Cardio Srl, Saluggia, Italy) at the authors' institution. Thirteen of these patients (six males, seven females; mean age 75.2 +/- 5.6 years) had previously undergone cardiac surgery and represented the study population. Preoperative, periprocedural and echocardiographic parameters, as well as clinical outcomes, were analyzed for all patients.

RESULTS

The primary procedure was AVR, using a bioprosthesis in six patients (46%) and coronary artery bypass grafting in seven (54%). The logistic EuroSCORE was 19.4 +/- 10.7%. Surgery was always performed via a full sternotomy; the mean implanted valve size was 23.6 +/- 1.3 mm (the previous valve size was 23.2 +/- 3.2 mm; p = 0.66). The mean cross-clamp time was 44 +/- 16 min, and the mean intensive care unit stay was 3.3 +/- 2.3 days. No intraoperative or in-hospital deaths occurred, and all patients were alive at a mean follow up of 8.5 months. Two postoperative events included transient ischemic attack in one patient, and the need for pacemaker implantation in one patient. On echocardiographic evaluation, no patient showed signs of paraprosthetic leak. The mean transvalvular gradient was 10.3 +/- 1.5 mmHg.

CONCLUSION

Use of the Perceval S sutureless AVR offers a fast and safe procedure, even in high-risk REDO surgery, providing a good hemodynamic performance with excellent clinical recovery, demonstrated at a follow up of six months. Although the sample size was limited, the results were encouraging and support the use of sutureless valves in the frame of REDO surgery for aortic valve disease.

摘要

研究背景与目的

本研究旨在报告在心脏再次手术(redo)时使用无缝合人工瓣膜进行主动脉瓣置换(AVR)的单中心队列患者的结果。

方法

2010年3月至2011年12月期间,共有83例患者在作者所在机构接受了使用Perceval S无缝合主动脉生物瓣膜(索林生物医学心脏有限公司,意大利萨卢贾)的AVR手术。其中13例患者(6例男性,7例女性;平均年龄75.2±5.6岁)此前接受过心脏手术,构成了研究人群。对所有患者的术前、围手术期和超声心动图参数以及临床结果进行了分析。

结果

主要手术为AVR,6例患者(46%)使用生物瓣膜,7例患者(54%)进行冠状动脉旁路移植术。逻辑欧洲心脏手术风险评估系统(EuroSCORE)为19.4±10.7%。手术均通过全胸骨切开术进行;植入瓣膜的平均尺寸为23.6±1.3mm(先前瓣膜尺寸为23.2±3.2mm;p = 0.66)。平均主动脉阻断时间为44±16分钟,平均重症监护病房停留时间为3.3±2.3天。术中或住院期间无死亡病例,所有患者在平均8.5个月的随访时均存活。术后有两个事件,包括1例患者发生短暂性脑缺血发作,1例患者需要植入起搏器。经超声心动图评估,无患者出现人工瓣膜旁漏迹象。平均跨瓣压差为10.3±1.5mmHg。

结论

使用Perceval S无缝合AVR即使在高风险的再次手术中也能提供快速且安全的手术过程,具有良好的血流动力学性能和出色的临床恢复情况,在六个月的随访中得到证实。尽管样本量有限,但结果令人鼓舞,支持在主动脉瓣疾病再次手术中使用无缝合瓣膜。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验