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帕金森病的最新进展:改善患者预后。

An update on Parkinson's disease: improving patient outcomes.

机构信息

Assistant Professor of Neurology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA.

Professor of Neurology, Molecular Pharmacology and Physiology, Director, Parkinson's Disease and Movement Disorders Center, University of South Florida, Tampa, FL.

出版信息

Am J Med. 2014 Jan;127(1):S3. doi: 10.1016/j.amjmed.2013.06.016.

DOI:10.1016/j.amjmed.2013.06.016
PMID:24384115
Abstract

Neurologists are faced with many challenges in caring for patients with Parkinson's disease (PD). This chronic, long-term illness that affects at least one million people in the United States requires a coordinated healthcare partnership between the physician and the patient. The importance of early diagnosis is essential to delaying disease progression and early diagnosis and intervention may be aided by recent advances in biomarkers, genomics, and imaging. A misdiagnosis or late diagnosis will lead to deteriorating patient health. Additionally, physicians should incorporate current guidelines into their treatment strategies, and awareness of the reasoning behind these guidelines is critical for appropriate use. Physicians should be up to date on identifying the most appropriate therapies based on emerging science and disease staging, and should implement patient education into their practice. Due to limitations for currently available therapies, adjunctive therapies may lead to improved outcomes in patients with PD. The use of multiple therapies can improve myriad symptoms, more so than a monotherapy. Knowledge of these therapies is critical to achieving best outcomes in patients with PD. This webcast will discuss the current challenges with PD clinical practice, clinical features of PD, the impact of treatment, future treatments for PD and improving patient outcomes.

摘要

神经科医生在照顾帕金森病(PD)患者时面临许多挑战。这种影响美国至少 100 万人的慢性、长期疾病需要医生和患者之间的协调医疗保健合作。早期诊断的重要性对于延缓疾病进展至关重要,而最近在生物标志物、基因组学和影像学方面的进展可能有助于早期诊断和干预。误诊或延迟诊断会导致患者健康状况恶化。此外,医生应将当前的指南纳入其治疗策略,并且了解这些指南背后的原因对于正确使用至关重要。医生应及时了解基于新兴科学和疾病分期的最适合的治疗方法,并应将患者教育纳入其实践。由于目前可用的治疗方法存在局限性,辅助治疗可能会改善 PD 患者的预后。使用多种疗法可以改善多种症状,比单一疗法更有效。了解这些疗法对于 PD 患者获得最佳疗效至关重要。本网络广播将讨论 PD 临床实践中的当前挑战、PD 的临床特征、治疗的影响、PD 的未来治疗方法以及改善患者预后。

相似文献

1
An update on Parkinson's disease: improving patient outcomes.帕金森病的最新进展:改善患者预后。
Am J Med. 2014 Jan;127(1):S3. doi: 10.1016/j.amjmed.2013.06.016.
2
Early diagnosis of Parkinson's disease: recommendations from diagnostic clinical guidelines.帕金森病的早期诊断:来自诊断临床指南的建议。
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Medication adherence and associated outcomes in medicare health maintenance organization-enrolled older adults with Parkinson's disease.医疗保险健康维护组织中患有帕金森病的老年参保者的药物依从性及相关结果
Mov Disord. 2008 Feb 15;23(3):359-65. doi: 10.1002/mds.21831.
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Implications for managed care for improving outcomes in Parkinson's disease: balancing aggressive treatment with appropriate care.管理式医疗对改善帕金森病治疗效果的意义:在积极治疗与恰当护理之间取得平衡。
Am J Manag Care. 2011 Oct;17 Suppl 12:S322-7.
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Current management of Parkinson's disease.帕金森病的当前管理
Ann Afr Med. 2010 Apr-Jun;9(2):55-61. doi: 10.4103/1596-3519.64743.
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Parkinson's disease. Update in diagnosis and symptom management.帕金森病。诊断与症状管理的最新进展。
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Advanced strategies for treatment of Parkinson's disease: the role of early treatment.帕金森病治疗的先进策略:早期治疗的作用。
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Parkinson's disease. More than meets the eye.帕金森病。远不止表面所见。
Adv Nurse Pract. 2003 Sep;11(9):42-4, 47-8, 51 passim.
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[Current strategies for the treatment of Parkinson's disease].[帕金森病的当前治疗策略]
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