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[喀麦隆杜阿拉市一家资源匮乏的城市地区医院的新生儿发病率和死亡率]

[Neonatal morbidity and mortality in a low-resource urban district hospital of Douala, Cameroon].

作者信息

Kedy Koum D, Exhenry C, Penda C-I, Nzima Nzima V, Pfister R E

机构信息

Unité de néonatologie, service de pédiatrie, hôpital de district de Bonassama, BP 9023, Douala, Cameroun; Département des sciences cliniques, faculté de médecine et de sciences pharmaceutiques, université de Douala, BP 2701, Douala, Cameroun.

24, chemin des Tulipiers, 1208 Genève, Suisse.

出版信息

Arch Pediatr. 2014 Feb;21(2):147-56. doi: 10.1016/j.arcped.2013.11.014. Epub 2013 Dec 30.

Abstract

INTRODUCTION

In countries with limited health-care resources, achieving the fourth Millennium Development Goal recommended by the WHO requires the reduction of neonatal mortality. Interventions at different levels of the community and the health-care system are needed, including in district hospitals.

METHOD

This was a descriptive study in the neonatal unit of the District Hospital of Bonassama/Douala in Cameroon that analyzed neonatal mortality and morbidity to discover possible intervention levers. The clinical, sociodemographic, and outcome data of hospitalized newborns were recorded from November 2009 to May 2012. The analysis was performed anonymously.

RESULTS

During 29 months, 813 infants were hospitalized; 71% were delivered naturally and 16% by cesarean section. Globally, 20% were premature, 55% were male, and 24% had a birth weight of less than 2500 g. At admission, 35% of the infants had hyperthermia and 29% hypothermia. The most common diagnoses were early infection (77%), late infection (22%), jaundice (17%), early adaptation disorders (18%), and hypoxic-ischemic encephalopathy (2.2%). The hospital mortality rate was 8% and the main diagnoses associated with death were: low birth weight, prematurity, hypothermia, and early adaptation disorders with and without encephalopathy. No excess mortality was found for neonates treated for infection.

CONCLUSION

In developing sub-Saharan countries, the main causes of neonatal mortality must be taken care of by hospitals at a peripheral district level. Epidemiological knowledge of neonatal diseases at the peripheral level (district) allows for an estimation of the requirements in terms of competence and equipment. Specific needs for transfer to a superior care unit can be estimated but the high transfer risk and the limited resources of the referral center should be taken into account.

摘要

引言

在医疗资源有限的国家,实现世界卫生组织建议的第四个千年发展目标需要降低新生儿死亡率。这需要在社区和医疗系统的不同层面进行干预,包括地区医院。

方法

这是一项在喀麦隆邦阿萨马/杜阿拉地区医院新生儿科进行的描述性研究,分析新生儿死亡率和发病率以发现可能的干预点。记录了2009年11月至2012年5月住院新生儿的临床、社会人口学和结局数据。分析是匿名进行的。

结果

在29个月期间,813名婴儿住院;71%为自然分娩,16%为剖宫产。总体而言,20%为早产儿,55%为男性,24%出生体重低于2500克。入院时,35%的婴儿体温过高,29%体温过低。最常见的诊断为早期感染(77%)、晚期感染(22%)、黄疸(17%)、早期适应障碍(18%)和缺氧缺血性脑病(2.2%)。医院死亡率为8%,与死亡相关的主要诊断为:低出生体重、早产、体温过低以及伴有或不伴有脑病的早期适应障碍。未发现感染治疗的新生儿有额外死亡情况。

结论

在撒哈拉以南的发展中国家,地区级周边医院必须关注新生儿死亡的主要原因。周边地区(地区级)对新生儿疾病的流行病学了解有助于评估能力和设备需求。可以估计向上级护理单位转诊的具体需求,但应考虑到转诊风险高和转诊中心资源有限的情况。

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