Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
Ann Arbor Veterans Affairs Center for Clinical Management Research, Ann Arbor, MI, USA; Department of Psychiatry and Behavioral Sciences University of Michigan, Ann Arbor, MI, USA; Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Gen Hosp Psychiatry. 2014 Mar-Apr;36(2):135-41. doi: 10.1016/j.genhosppsych.2013.11.008. Epub 2013 Dec 4.
The objective was to estimate the prevalence of both dementia and depression among community-dwelling older Americans and to determine if hospitalization is independently associated with dementia or depression in this population.
This cross-sectional study utilized data from a nationally representative, population-based sample of 7197 community-dwelling adults ≥ 65 years old interviewed in 2011 as part of the National Health and Aging Trends Study. Information on hospitalizations was obtained from self- or proxy-report. Possible and probable dementia was assessed according to a validated algorithm. Depressive symptoms were assessed with the Patient Health Questionnaire-2.
An estimated 3.1 million community-dwelling older Americans may have dementia, and approximately 5.3 million may have substantial depressive symptoms. After adjusting for demographic and social characteristics, medical diagnoses, smoking history, serious falls and pain symptoms, being hospitalized in the previous year was independently associated with greater odds of probable dementia (odds ratio [OR]: 1.42, 95% confidence interval [95% CI]: 1.16-1.73) and substantial depressive symptoms (OR: 1.60, 95% CI: 1.29-1.99).
Dementia and depression are common in community-dwelling older Americans, and hospitalization is associated with these conditions. Additional research increasing understanding of the bidirectional relationship between hospitalizations, dementia and depression, along with targeted interventions to reduce hospitalizations, is needed.
本研究旨在评估美国社区居住的老年人中痴呆和抑郁的患病率,并确定在该人群中,住院是否与痴呆或抑郁独立相关。
本横断面研究利用了 2011 年全国健康老龄化趋势研究中对 7197 名≥65 岁社区居住成年人进行的全国代表性、基于人群的样本数据。住院信息来自自我报告或代理报告。根据经过验证的算法评估可能和可能的痴呆。使用患者健康问卷-2 评估抑郁症状。
估计有 310 万美国社区居住的老年人可能患有痴呆症,约有 530 万人可能患有严重的抑郁症状。在调整人口统计学和社会特征、医疗诊断、吸烟史、严重跌倒和疼痛症状后,去年住院与更高的可能痴呆症几率(比值比 [OR]:1.42,95%置信区间 [95%CI]:1.16-1.73)和严重抑郁症状(OR:1.60,95%CI:1.29-1.99)独立相关。
痴呆症和抑郁症在社区居住的美国老年人中很常见,住院与这些情况有关。需要进一步研究,以增进对住院、痴呆和抑郁之间的双向关系的理解,并采取有针对性的干预措施来减少住院。