Saliev Timur, Tachibana Katsuro, Bulanin Denis, Mikhalovsky Sergey, Whitby Ray D L
Department of Regenerative Medicine and Artificial Organs, PE.
Department of Anatomy, Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Fukuoka 814-0180, Japan.
Front Biosci (Elite Ed). 2014 Jan 1;6(1):175-84. doi: 10.2741/e700.
Bio-effects mediated by non-ionizing electromagnetic fields (EMF) have become a hot topic of research in the last decades. This interest has been triggered by a growing public concern about the rapid expansion of telecommunication devices and possible consequences of their use on human health. Despite a feasibility study of potential negative impacts, the therapeutic advantages of EMF could be effectively harnessed for the treatment of cancer and other diseases. This review aims to examine recent findings relating to the mechanisms of action underlying the bio-effects induced by non-ionizing EMF. The potential of non-thermal and thermal effects is discussed in the context of possible applications for the induction of apoptosis, formation of reactive oxygen species, and increase of membrane permeability in malignant cells. A special emphasis has been put on the combination of EMF with magnetic nano-particles and ultrasound for cancer treatment. The review encompasses both human and animal studies.
在过去几十年中，非电离电磁场（EMF）介导的生物效应已成为一个热门研究话题。公众对电信设备的迅速普及及其使用可能对人类健康产生的后果日益关注，引发了这种兴趣。尽管对潜在负面影响进行了可行性研究，但EMF的治疗优势可有效用于癌症和其他疾病的治疗。本综述旨在研究与非电离EMF诱导生物效应的作用机制相关的最新发现。在诱导恶性细胞凋亡、形成活性氧以及增加膜通透性的可能应用背景下，讨论了非热效应和热效应的潜力。特别强调了EMF与磁性纳米颗粒和超声联合用于癌症治疗。该综述涵盖了人体研究和动物研究。
