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Ramosetron in irritable bowel syndrome with diarrhea: new hope or the same old story?

作者信息

Grover Madhusudan, Camilleri Michael

机构信息

Clinical Enteric Neuroscience Translational and Epidemiological Research, Mayo Clinic, Rochester, Minnesota.

出版信息

Clin Gastroenterol Hepatol. 2014 Jun;12(6):960-2. doi: 10.1016/j.cgh.2013.12.025. Epub 2014 Jan 3.

Abstract
摘要

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本文引用的文献

1
Effect of ramosetron on stool consistency in male patients with irritable bowel syndrome with diarrhea.
Clin Gastroenterol Hepatol. 2014 Jun;12(6):953-9.e4. doi: 10.1016/j.cgh.2013.11.024. Epub 2013 Dec 4.
2
A 9-year evaluation of temporal trends in alosetron postmarketing safety under the risk management program.
Therap Adv Gastroenterol. 2013 Sep;6(5):344-57. doi: 10.1177/1756283X13491798.
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Long-term efficacy and safety of ramosetron in the treatment of diarrhea-predominant irritable bowel syndrome.
Clin Exp Gastroenterol. 2013 Jul 25;6:123-8. doi: 10.2147/CEG.S32721. Print 2013.
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Current and future pharmacological treatments for diarrhea-predominant irritable bowel syndrome.
Expert Opin Pharmacother. 2013 Jun;14(9):1151-60. doi: 10.1517/14656566.2013.794223. Epub 2013 Apr 27.
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Randomised clinical trial: alosetron improves quality of life and reduces restriction of daily activities in women with severe diarrhoea-predominant IBS.
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The risk of ischaemic colitis in irritable bowel syndrome patients treated with serotonergic therapies.
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Alosetron, cilansetron and tegaserod modify mesenteric but not colonic blood flow in rats.
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Efficacy of 5-HT3 antagonists and 5-HT4 agonists in irritable bowel syndrome: systematic review and meta-analysis.
Am J Gastroenterol. 2009 Jul;104(7):1831-43; quiz 1844. doi: 10.1038/ajg.2009.223. Epub 2009 May 26.

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