Nomura Kazushi
Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo.
Nihon Rinsho. 2013 Nov;71(11):1954-9.
Diabetes mellitus increases approximately twice the risk of cardiovascular events even in older patients. In addition, cardiovascular disease is one of the most important causes of death in older patients with diabetes. However, any large-scale clinical trials have never demonstrated that strict glycemic control could lead to reduction in cardiovascular risk. On the other hand, several studies have shown as follows: Glycemic control in early stage might be important for suppression of cardiovascular events in future. Avoiding hypoglycemia is most important for elderly patients with long history of diabetes and atherosclerosis.
即使在老年患者中,糖尿病也会使心血管事件的风险增加约两倍。此外,心血管疾病是老年糖尿病患者最重要的死亡原因之一。然而,任何大规模临床试验都从未证明严格的血糖控制能降低心血管风险。另一方面,多项研究表明:早期的血糖控制对于未来抑制心血管事件可能很重要。对于有长期糖尿病和动脉粥样硬化病史的老年患者来说,避免低血糖最为重要。