Sakurai Takashi
Center for Comprehensive Care and Research on Memory Disorders, National Center for Geriatrics and Gerontology.
Nihon Rinsho. 2013 Nov;71(11):1960-4.
Cognitive decline in diabetes impairs the activity of daily living and shortens the healthy life expectancy. Once diabetes is accompanied by demented disorders, it becomes difficult to achieve good control of diabetes. Treatment for diabetes and demented disease should be provided concomitantly, because cognitive dysfunction worsens diabetic control and hyperglycemia worsens cognitive function vice versa, resulting in increased risks of acute metabolic failure. Compliance to medical treatment of diabetes is seriously impaired in the elderly with cognitive decline. Comprehensive approach with several medical specialists and care stuffs is thus needed. This manuscript briefly summaries the recent evidence for target of glycemic control and appropriate use of anti-diabetic medication in diabetic elderly with cognitive impairment.
糖尿病患者的认知功能下降会损害日常生活活动能力，并缩短健康预期寿命。一旦糖尿病伴有痴呆症，就很难实现对糖尿病的良好控制。糖尿病和痴呆症应同时进行治疗，因为认知功能障碍会使糖尿病控制恶化，而高血糖会使认知功能恶化，反之亦然，从而增加急性代谢衰竭的风险。认知功能下降的老年人对糖尿病药物治疗的依从性严重受损。因此，需要多学科医学专家和护理人员采取综合治疗方法。本文简要总结了近期关于认知障碍老年糖尿病患者血糖控制目标和合理使用抗糖尿病药物的证据。
