Faculty of Chemistry and Center for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Universitaetsstr. 5, D-45141 Essen, Germany.
Chem Commun (Camb). 2014 Mar 14;50(21):2711-4. doi: 10.1039/c3cc48633h.
Rapid parallel detection of two cytokines (IL-6 and IL-8) with femtogram sensitivity in a simple direct dot-blot assay is demonstrated. The microspectroscopic SERS acquisition scheme employs rationally designed, hydrophilically stabilized Au-Ag nanoshells as SERS labels, which are optimized for signal enhancement upon red laser excitation.
本文展示了一种简单的直接点印迹分析方法，可实现对两种细胞因子（IL-6 和 IL-8）进行纳升级灵敏度的快速平行检测。该微光谱 SERS 采集方案采用了经过合理设计的、亲水性稳定的 Au-Ag 纳米壳作为 SERS 标记物，这些标记物在红光激光激发下具有最佳的信号增强效果。
