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1例转化为白血病的肝脾T细胞淋巴瘤的组织病理学、免疫表型及临床特点与演变

Histopathological, immunophenotypic and clinical particularities and evolution of a case of hepatosplenic T-cell lymphoma in transformation to leukemia.

作者信息

Benedek Lázár Erzsébet, Köpeczi Judit Beáta, Tunyogi Aliz Beáta, Kakucs Enikő, Horváth Emőke, Turcu M, Benedek I

机构信息

Department of Pathology, Faculty of General Medicine, University of Medicine and Pharmacy of Tirgu Mures, Romania;

出版信息

Rom J Morphol Embryol. 2013;54(4):1135-9.

PMID:24399013
Abstract

We present the possibilities of diagnosis correlating the pathological, immunophenotyping and clinical aspects of a rare case of T-cell lymphoma in a 23-year-old patient with leukemic transformation. In our consideration, it is very important to describe this case because in the literature there are very few cases presented and the treatment of this type of lymphoma does not present optimal results, the evolution of the patients being from three months to two years. The treatment modality that gives the possibility to prolong survival and cure is hematopoietic stem cell transplantation.

摘要

我们展示了对一名23岁白血病转化的T细胞淋巴瘤罕见病例的病理、免疫表型和临床方面进行诊断关联的可能性。在我们看来,描述这个病例非常重要,因为文献中报道的此类病例很少,且这种淋巴瘤的治疗效果并不理想,患者的病程从三个月到两年不等。能够延长生存期并实现治愈的治疗方式是造血干细胞移植。

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引用本文的文献

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Hepatosplenic T cell lymphoma: a unifying entity in a patient with hemolytic anemia, massive splenomegaly, and liver dysfunction.肝脾T细胞淋巴瘤:一例合并溶血性贫血、巨脾和肝功能不全患者的统一诊断实体
Clin J Gastroenterol. 2018 Oct;11(5):364-370. doi: 10.1007/s12328-018-0869-x. Epub 2018 May 15.