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锯叶棕提取物联合喹诺酮类药物治疗慢性细菌性前列腺炎。一项长期观察性研究的初步结果。

Serenoa repens extract additionally to quinolones in the treatment of chronic bacterial prostatitis. The preliminary results of a long term observational study.

作者信息

Stamatiou Konstantinos, Pierris Nikolaos

机构信息

Urology Department, Tzaneio Hospital, Pireas.

出版信息

Arch Ital Urol Androl. 2013 Dec 31;85(4):190-6. doi: 10.4081/aiua.2013.4.190.

DOI:10.4081/aiua.2013.4.190
PMID:24399120
Abstract

INTRODUCTION

Chronic prostatitis displays a variety of symptoms (mainly local pain exhibiting variability in origin and intensity). The purpose of this article is to briefly present the preliminary results of our study examining the role of phytotherapeutic agents in the treatment of chronic prostatitis patients.

MATERIALS AND METHODS

The study included in total fifty-six consecutive patients who visited the outpatient department. Subjects were randomized into two groups. Subjects in the first group (28 patients) received prulifloxacin 600 mg for 15 days, while subjects in the second group (28 patients) received prulifloxacin 600 mg for 15 days and Serenoa repens extract for 8 weeks. The response was tested using laboratory and clinical criteria.

RESULTS

We found statistically significant differences between the two groups regarding pain regression and no statistically significant regarding bacterial eradication. Moreover however while sexual dysfunction improvement was equally achieved in both groups, improvement of urinary symptoms was more evident in the 2nd group especially after the completion of the antibiotic treatment.

CONCLUSIONS

Serenoa repens extract for 8 weeks seems to improve prostatitis related pain. Further randomized, placebo-controlled studies are needed to substantiate safer conclusions.

摘要

引言

慢性前列腺炎表现出多种症状(主要是局部疼痛,其起源和强度具有变异性)。本文的目的是简要介绍我们研究植物治疗剂在慢性前列腺炎患者治疗中作用的初步结果。

材料与方法

该研究共纳入了56名连续就诊于门诊的患者。受试者被随机分为两组。第一组(28名患者)接受600毫克普卢利沙星治疗15天,而第二组(28名患者)接受600毫克普卢利沙星治疗15天,并接受8周的锯叶棕提取物治疗。使用实验室和临床标准来测试疗效。

结果

我们发现两组在疼痛消退方面存在统计学显著差异,而在细菌清除方面无统计学显著差异。此外,虽然两组在性功能改善方面相当,但第二组的尿路症状改善更为明显,尤其是在抗生素治疗结束后。

结论

8周的锯叶棕提取物似乎能改善前列腺炎相关疼痛。需要进一步进行随机、安慰剂对照研究以证实更可靠的结论。

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