Zacharia George Sarin, Ray Roji, Sivaprasad Punnaveetil, Kolassery Sandesh, Ramachandran Thazhath Mavali
Department of Gastroenterology, Government Medical College, Medical College P.O., Calicut, 673 008, India.
Indian J Gastroenterol. 2014 May;33(3):289-91. doi: 10.1007/s12664-013-0438-7. Epub 2014 Jan 8.
Bleeding manifestations, usually cutaneous or gastrointestinal - are common in liver cirrhosis. Spontaneous intracerebral and intramuscular bleeds are reported uncommonly, often associated with gross hepatic dysfunction and severely deranged hemostatic parameters, and are often markers to imminent mortality. Male sex, alcoholic etiology, significant thrombocytopenia, severe coagulopathy, and advanced liver disease are common denominators in patients with spontaneous intramuscular bleed. We here report three cases of spontaneous muscle hematomas complicating hepatic cirrhosis. To the best of our knowledge, this is the largest single center series reporting spontaneous muscle hematomas complicating cirrhosis from the Indian subcontinent.
出血表现通常为皮肤或胃肠道出血，在肝硬化患者中很常见。自发性脑内出血和肌肉出血的报道较少见，常与严重肝功能不全和严重紊乱的止血参数相关，且往往是即将死亡的标志。男性、酒精性病因、明显血小板减少、严重凝血障碍和晚期肝病是自发性肌肉出血患者的共同特征。我们在此报告三例肝硬化并发自发性肌肉血肿的病例。据我们所知，这是来自印度次大陆报道肝硬化并发自发性肌肉血肿的最大单中心系列病例。
