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花生四烯酸盐对小鼠膈肌中的电生性钠钾泵有积极作用。

Arachidonate has a positive effect on the electrogenic sodium-potassium pump in the mouse diaphragm.

作者信息

Vyskocil P, Zemková H, Teisinger J, Vyskocil F

出版信息

Physiol Bohemoslov. 1987;36(2):167-9.

PMID:2440070
Abstract

Sodium arachidonate 5 X 10(-5) mol X l-1 shortened the time course of hyperpolarization caused by the electrogenic Na+-K+ pump in intact muscle fibres in the mouse diaphragm preincubated in a K+-free physiological solution. Contrary to experiments on membrane fragments, no inhibition of the ouabain-sensitive Na+-K+ ATPase was observed. It is unlikely that the arachidonate may be identical with the endogenous "ouabain-like" substance (Bidard et al. 1984).

摘要

花生四烯酸钠5×10⁻⁵摩尔×升⁻¹缩短了在无钾生理溶液中预孵育的小鼠膈肌完整肌纤维中由电生性钠钾泵引起的超极化时间进程。与对膜片段的实验相反,未观察到哇巴因敏感的钠钾ATP酶受到抑制。花生四烯酸盐不太可能与内源性“类哇巴因”物质相同(Bidard等人,1984年)。

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Arachidonate has a positive effect on the electrogenic sodium-potassium pump in the mouse diaphragm.花生四烯酸盐对小鼠膈肌中的电生性钠钾泵有积极作用。
Physiol Bohemoslov. 1987;36(2):167-9.
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