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[未识别的青少年皮肌炎合并全身钙质沉着症:喀麦隆的一例病例报告]

[Unrecognized juvenile dermatomyositis complicated by calcinosis universalis: a case report from Cameroon].

作者信息

Mandengue C E, Nouedoui C, Atangana P J A

机构信息

Médecine interne, Hôpital Général de Yaoundé, BP 13650, Yaoundé, Cameroun, Afrique.

Laboratoire d'anatomie-pathologie, Institut Pasteur du Cameroun, Yaoundé, Cameroun, Afrique.

出版信息

Med Sante Trop. 2013 Oct-Dec;23(4):458-61. doi: 10.1684/mst.2013.0248.

Abstract

Juvenile dermatomyositis is a rare autoimmune disease that causes inflammation of the skin and muscles. Calcinosis may complicate its course, especially when the diagnosis is late or the corticosteroid therapy inadequate. In those cases, significant joint disability may occur. Few cases are reported in sub-Saharan Africa, probably because it is rarely recognized in these areas. We report the first Cameroonian case, occurring in a 9-year-old girl. Although she sought treatment early in the disease course, the dermatomyositis was diagnosed quite late, after the onset of calcinosis universalis and severe disability. Early diagnosis of the disease and effective treatment are essential to prevent calcinosis universalis from complicating this disease in children.

摘要

幼年皮肌炎是一种罕见的自身免疫性疾病,可导致皮肤和肌肉炎症。钙质沉着可能使病情复杂化,尤其是在诊断延迟或皮质类固醇治疗不足时。在这些情况下,可能会出现严重的关节残疾。撒哈拉以南非洲地区报告的病例很少,可能是因为在这些地区该病很少被识别。我们报告了喀麦隆的首例病例,发生在一名9岁女孩身上。尽管她在病程早期就寻求治疗,但皮肌炎的诊断却很晚,是在泛发性钙质沉着和严重残疾出现之后。该病的早期诊断和有效治疗对于预防泛发性钙质沉着使儿童病情复杂化至关重要。

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