老年患者血管内注射造影剂后发生造影剂诱导的急性肾损伤的发生率及风险。
Incidence and risk of developing contrast-induced acute kidney injury following intravascular contrast administration in elderly patients.
作者信息
Song Wei, Zhang Tuo, Pu Jun, Shen Linghong, He Ben
机构信息
Department of Cardiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China.
出版信息
Clin Interv Aging. 2014;9:85-93. doi: 10.2147/CIA.S55157. Epub 2013 Dec 31.
BACKGROUND
The purpose of this meta-analysis was to evaluate the epidemiology of contrast-induced acute kidney injury (CI-AKI) in the elderly.
METHODS
A literature review was undertaken to determine the incidence of CI-AKI in individuals receiving intravascular contrast medium in the hospital setting.
RESULTS
Twenty-two studies with 186,455 patients were identified. The pooled incidence of CI-AKI was 13.6% in 67,831 patients older than 65 years of age (95% confidence interval [CI] 10.1-18.2, I(2) =0.496). The pooled odds ratio of CI-AKI in the elderly was 2.55 (95% CI 1.85-3.52, I(2) =0.34). The high incidence of CI-AKI in the elderly was consistent across different administration route subgroups (intracoronary contrast medium group, 15.5% [95% CI 10.3-22.6]; intravenous contrast medium group, 12.4% [95% CI 8.0-18.8]).
CONCLUSION
Elderly patients are at greater risk for developing CI-AKI.
背景
本荟萃分析旨在评估老年患者中对比剂诱导的急性肾损伤（CI-AKI）的流行病学情况。
方法
进行文献综述以确定在医院环境中接受血管内造影剂的个体中CI-AKI的发生率。
结果
共纳入22项研究，涉及186,455例患者。67,831例65岁以上患者中CI-AKI的合并发生率为13.6%（95%置信区间[CI] 10.1 - 18.2，I² = 0.496）。老年患者中CI-AKI的合并比值比为2.55（95% CI 1.85 - 3.52，I² = 0.34）。在不同给药途径亚组中，老年患者CI-AKI的高发生率是一致的（冠状动脉内造影剂组，15.5% [95% CI 10.3 - 22.6]；静脉造影剂组，12.4% [95% CI 8.0 - 18.8]）。
结论
老年患者发生CI-AKI的风险更高。
Zotero 插件