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后路和侧方钢板固定的侧路腰椎间融合构建的生物力学:实验室研究。

Biomechanics of lateral lumbar interbody fusion constructs with lateral and posterior plate fixation: laboratory investigation.

机构信息

San Antonio, Texas;

出版信息

J Neurosurg Spine. 2014 Mar;20(3):291-7. doi: 10.3171/2013.11.SPINE13617. Epub 2014 Jan 3.

Abstract

OBJECT

Lumbar interbody fusion is indicated in the treatment of degenerative conditions. Laterally inserted interbody cages significantly decrease range of motion (ROM) compared with other cages. Supplemental fixation options such as lateral plates or spinous process plates have been shown to provide stability and to reduce morbidity. The authors of the current study investigate the in vitro stability of the interbody cage with a combination of lateral and spinous process plate fixation and compare this method to the established bilateral pedicle screw fixation technique.

METHODS

Ten L1-5 specimens were evaluated using multidirectional nondestructive moments (± 7.5 N · m), with a custom 6 degrees-of-freedom spine simulator. Intervertebral motions (ROM) were measured optoelectronically. Each spine was evaluated under the following conditions at the L3-4 level: intact; interbody cage alone (stand-alone); cage supplemented with lateral plate; cage supplemented with ipsilateral pedicle screws; cage supplemented with bilateral pedicle screws; cage supplemented with spinous process plate; and cage supplemented with a combination of lateral plate and spinous process plate. Intervertebral rotations were calculated, and ROM data were normalized to the intact ROM data.

RESULTS

The stand-alone laterally inserted interbody cage significantly reduced ROM with respect to the intact state in flexion-extension (31.6% intact ROM, p < 0.001), lateral bending (32.5%, p < 0.001), and axial rotation (69.4%, p = 0.002). Compared with the stand-alone condition, addition of a lateral plate to the interbody cage did not significantly alter the ROM in flexion-extension (p = 0.904); however, it was significantly decreased in lateral bending and axial rotation (p < 0.001). The cage supplemented with a lateral plate was not statistically different from bilateral pedicle screws in lateral bending (p = 0.579). Supplemental fixation using a spinous process plate was not significantly different from bilateral pedicle screws in flexion-extension (p = 0.476). The combination of lateral plate and spinous process plate was not statistically different from the cage supplemented with bilateral pedicle screws in all the loading modes (p ≥ 0.365).

CONCLUSIONS

A combination of lateral and spinous process plate fixation to supplement a laterally inserted interbody cage helps achieve rigidity in all motion planes similar to that achieved with bilateral pedicle screws.

摘要

目的

腰椎体间融合术用于治疗退行性疾病。与其他椎间笼相比,侧向插入椎间笼显著降低了活动范围(ROM)。已经证明,附加固定选项,如侧板或棘突板,可提供稳定性并降低发病率。当前研究的作者研究了侧向和棘突板固定相结合的椎间笼的体外稳定性,并将这种方法与已建立的双侧椎弓根螺钉固定技术进行了比较。

方法

使用定制的 6 自由度脊柱模拟器评估 10 个 L1-5 标本,施加多向非破坏性力矩(±7.5 N·m)。使用光电方法测量椎间运动(ROM)。在 L3-4 水平下,每个脊柱在以下条件下进行评估:完整;单独椎间笼(独立);笼中补充侧板;笼中补充同侧椎弓根螺钉;笼中补充双侧椎弓根螺钉;笼中补充棘突板;笼中补充侧板和棘突板的组合。计算椎间旋转,并将 ROM 数据归一化为完整 ROM 数据。

结果

独立的侧向插入椎间笼在屈伸(31.6%完整 ROM,p<0.001)、侧屈(32.5%,p<0.001)和轴向旋转(69.4%,p=0.002)方面与完整状态相比显著降低了 ROM。与独立状态相比,向椎间笼中添加侧板在屈伸时并未显著改变 ROM(p=0.904);然而,在侧屈和轴向旋转时,ROM 显著降低(p<0.001)。用侧板补充的笼在侧屈时与双侧椎弓根螺钉无统计学差异(p=0.579)。用棘突板进行补充固定在屈伸时与双侧椎弓根螺钉无统计学差异(p=0.476)。在所有加载模式下,侧板和棘突板的组合与补充双侧椎弓根螺钉的笼均无统计学差异(p≥0.365)。

结论

侧向插入椎间笼中侧向和棘突板固定的组合有助于在所有运动平面上实现与双侧椎弓根螺钉相似的刚性。

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