• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

SNPs in the kallikrein gene region associated with prostate cancer risk: true cause or association by design?

作者信息

Eeles R, Giles G, Neal D, Hamdy F, Donovan J, Muir K, Easton D

出版信息

Nat Genet. 2008 Sep 1;40(9):1035-6. doi: 10.1038/ng0908-1035.

DOI:10.1038/ng0908-1035
PMID:24409082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3882634/
Abstract
摘要

相似文献

1
SNPs in the kallikrein gene region associated with prostate cancer risk: true cause or association by design?激肽释放酶基因区域的单核苷酸多态性与前列腺癌风险相关：是真正的病因还是设计上的关联？
Nat Genet. 2008 Sep 1;40(9):1035-6. doi: 10.1038/ng0908-1035.
2
Tagging SNPs in the kallikrein genes 3 and 2 on 19q13 and their associations with prostate cancer in men of European origin.对19号染色体长臂1区3带激肽释放酶基因3和2中的单核苷酸多态性进行分型及其与欧洲裔男性前列腺癌的关联。
Hum Genet. 2007 Nov;122(3-4):251-9. doi: 10.1007/s00439-007-0394-3. Epub 2007 Jun 26.
3
Association of kallikrein gene polymorphisms with intracranial aneurysms.激肽释放酶基因多态性与颅内动脉瘤的关联。
Stroke. 2007 Oct;38(10):2670-6. doi: 10.1161/STROKEAHA.107.486225. Epub 2007 Aug 30.
4
Human kallikrein-2 gene and protein expression predicts prostate cancer at repeat biopsy.人激肽释放酶-2基因和蛋白表达可预测重复活检时的前列腺癌。
Springerplus. 2014 Jun 11;3:295. doi: 10.1186/2193-1801-3-295. eCollection 2014.
5
Twenty-year Risk of Prostate Cancer Death by Midlife Prostate-specific Antigen and a Panel of Four Kallikrein Markers in a Large Population-based Cohort of Healthy Men.基于大规模健康男性人群队列，通过中年前列腺特异性抗原和一组四种激肽释放酶标志物预测前列腺癌死亡的20年风险
Eur Urol. 2018 Jun;73(6):941-948. doi: 10.1016/j.eururo.2018.02.016. Epub 2018 Mar 5.
6
Common variation in Kallikrein genes KLK5, KLK6, KLK12, and KLK13 and risk of prostate cancer and tumor aggressiveness. Kallikrein 基因 KLK5、KLK6、KLK12 和 KLK13 的常见变异与前列腺癌风险和肿瘤侵袭性的关系。
Urol Oncol. 2013 Jul;31(5):635-43. doi: 10.1016/j.urolonc.2011.05.011. Epub 2011 Jul 8.
7
Predictive value of four kallikrein markers for pathologically insignificant compared with aggressive prostate cancer in radical prostatectomy specimens: results from the European Randomized Study of Screening for Prostate Cancer section Rotterdam.在根治性前列腺切除标本中，四种激肽释放酶标志物对与侵袭性前列腺癌相比病理意义不显著的前列腺癌的预测价值：来自欧洲前列腺癌筛查随机研究鹿特丹分部的结果
Eur Urol. 2013 Nov;64(5):693-9. doi: 10.1016/j.eururo.2013.04.040. Epub 2013 May 2.
8
Kallikrein markers performance in pretreatment blood to predict early prostate cancer recurrence and metastasis after radical prostatectomy among very high-risk men.在极高危男性中，前列腺癌根治术前血液中激肽释放酶标志物的表现可预测术后早期复发和转移。
Prostate. 2020 Jan;80(1):51-56. doi: 10.1002/pros.23916. Epub 2019 Oct 11.
9
Identification and structure of the rat true tissue kallikrein gene expressed in the kidney.
J Biochem. 1989 May;105(5):834-40. doi: 10.1093/oxfordjournals.jbchem.a122754.
10
Genetic association of the KLK4 locus with risk of prostate cancer.KLK4 基因座与前列腺癌风险的遗传关联。
PLoS One. 2012;7(9):e44520. doi: 10.1371/journal.pone.0044520. Epub 2012 Sep 6.

引用本文的文献

1
Blood biomarker levels to aid discovery of cancer-related single-nucleotide polymorphisms: kallikreins and prostate cancer.血液生物标志物水平有助于发现与癌症相关的单核苷酸多态性：激肽释放酶与前列腺癌。
Cancer Prev Res (Phila). 2010 May;3(5):611-9. doi: 10.1158/1940-6207.CAPR-09-0206. Epub 2010 Apr 27.
2
A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33.对 19q13.33 染色体上 KLK15-KLK3-KLK2 基因座进行全面重测序分析。
Hum Genet. 2010 Jan;127(1):91-9. doi: 10.1007/s00439-009-0751-5. Epub 2009 Oct 13.
3
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.通过全基因组关联研究鉴定出七个新的前列腺癌易感基因座。
Nat Genet. 2009 Oct;41(10):1116-21. doi: 10.1038/ng.450. Epub 2009 Sep 20.
4
Intermediacy and gene-environment interaction: the example of CHRNA5-A3 region, smoking, nicotine dependence, and lung cancer.中介作用与基因-环境相互作用：以CHRNA5-A3区域、吸烟、尼古丁依赖和肺癌为例。
J Natl Cancer Inst. 2008 Nov 5;100(21):1488-91. doi: 10.1093/jnci/djn380. Epub 2008 Oct 28.

本文引用的文献

1
Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium.一项国际研究证实多个新型前列腺癌易感基因座：PRACTICAL联盟
Cancer Epidemiol Biomarkers Prev. 2008 Aug;17(8):2052-61. doi: 10.1158/1055-9965.EPI-08-0317.
2
Multiple newly identified loci associated with prostate cancer susceptibility.多个新发现的与前列腺癌易感性相关的基因座。
Nat Genet. 2008 Mar;40(3):316-21. doi: 10.1038/ng.90. Epub 2008 Feb 10.
3
Prediction of prostate cancer for patients receiving finasteride: results from the Prostate Cancer Prevention Trial.非那雄胺治疗患者前列腺癌的预测：来自前列腺癌预防试验的结果。
J Clin Oncol. 2007 Jul 20;25(21):3076-81. doi: 10.1200/JCO.2006.07.6836.
4
Long-term prediction of prostate cancer up to 25 years before diagnosis of prostate cancer using prostate kallikreins measured at age 44 to 50 years.利用44至50岁时检测的前列腺激肽释放酶对前列腺癌进行长达25年的长期预测，直至前列腺癌确诊前。
J Clin Oncol. 2007 Feb 1;25(4):431-6. doi: 10.1200/JCO.2006.06.9351.
5
PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility.前列腺特异性抗原/激肽释放酶3 AREI启动子多态性改变雄激素受体结合并与前列腺癌易感性相关。
Carcinogenesis. 2007 May;28(5):1032-9. doi: 10.1093/carcin/bgl236. Epub 2006 Dec 6.