Su Lingqia, Chen Sheng, Wu Jing
State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Wei Sheng Wu Xue Bao. 2013 Oct 4;53(10):1011-7.
In recent years, with the development of biotechnology, the molecular mechanism of the secretion pathways in Escherichia coli is clearer and clearer, and it becomes one of the most effective methods to use E. coli expression system for extracellular production of recombinant proteins. This review discusses recent advances in the secretion mechanism and application of E. coli alpha-hemolysin secretion pathway.
近年来，随着生物技术的发展，大肠杆菌分泌途径的分子机制越来越清晰，利用大肠杆菌表达系统进行重组蛋白胞外生产成为最有效的方法之一。本文综述了大肠杆菌α-溶血素分泌途径的分泌机制及应用的研究进展。
