Cingü Abdullah Kürşat, Kaya Savaş, Çınar Yasin, Şahin Muhammed, Türkçü Fatih Mehmet, Yüksel Harun, Murat Mehmet, Çaça İhsan
Department of Ophthalmology, Dicle University Faculty of Medicine , 21280, Diyarbakir , Turkey and.
Semin Ophthalmol. 2015 May;30(3):197-201. doi: 10.3109/08820538.2013.839804. Epub 2014 Jan 10.
The aim of this study was to comparatively evaluate the vitreous depth (VD) of keratoconic eyes in patients with or without vernal keratoconjunctivitis (VKC).
Eighty eyes of 80 consecutive keratoconus (KC) patients and 40 emmetropic control subjects were enrolled. KC patients were divided into two groups according to accompanying VKC (VKC-KC group and KC group). Mean outcome measures were best-corrected visual acuity (BCVA), spherical equivalent (SE), mean keratometry (Km), intraocular pressure (IOP), and axial length (AL) and its components. The eyes with the highest Km were selected for statistical analysis for each participant.
There were 50, 30, and 40 patients in the VKC-KC group, KC group, and control group respectively. The KC group and VKC-KC group were similar in BCVA, SE, Km, CCT, ACD, LT, and IOP (p>0.05). The mean ACD was significantly lower in the control group when compared with the KC group and VKC-KC group. The mean AL and VD were significantly higher in VKC-KC group than those of KC group and the control group, whereas similar in KC and control groups (p>0.05).
In the current study we showed that VKC-associated KC patients have significantly longer AL and VD when compared with KC patients without VKC. Posterior segment elongation in VKC-KC group may be associated with the type IV collagen destruction due to chronic longstanding inflammation in VKC patients.
本研究旨在比较评估患有或不患有春季角结膜炎（VKC）的圆锥角膜患者的玻璃体深度（VD）。
纳入80例连续圆锥角膜（KC）患者的80只眼和40例正视对照者。KC患者根据是否伴有VKC分为两组（VKC-KC组和KC组）。主要观察指标为最佳矫正视力（BCVA）、等效球镜度（SE）、平均角膜曲率（Km）、眼压（IOP）、眼轴长度（AL）及其组成部分。为每位参与者选择Km最高的眼进行统计分析。
VKC-KC组、KC组和对照组分别有50例、30例和40例患者。KC组和VKC-KC组在BCVA、SE、Km、中央角膜厚度（CCT）、前房深度（ACD）、晶状体厚度（LT）和IOP方面相似（p>0.05）。与KC组和VKC-KC组相比，对照组的平均ACD显著更低。VKC-KC组的平均AL和VD显著高于KC组和对照组，而KC组和对照组相似（p>0.05）。
在本研究中，我们发现与不伴有VKC的KC患者相比，伴有VKC的KC患者的AL和VD显著更长。VKC-KC组的眼后段延长可能与VKC患者慢性长期炎症导致的IV型胶原破坏有关。
