Cerebrovascular and Endovascular Division, Department of Neurosurgery, Tufts Medical Center and Tufts University School of Medicine, 800 Washington Street #178, Proger 7, Boston, MA 02111, USA.
Cerebrovascular and Endovascular Division, Department of Neurosurgery, Tufts Medical Center and Tufts University School of Medicine, 800 Washington Street #178, Proger 7, Boston, MA 02111, USA.
J Clin Neurosci. 2014 Jun;21(6):1024-8. doi: 10.1016/j.jocn.2013.10.017. Epub 2013 Nov 11.
The flow-diverting Pipeline Embolization Device (PED; ev3 Neurovascular, Irvine, CA, USA) provides proven flow diversion for intracranial wide-necked and fusiform aneurysms. The tendency of the PED to migrate and foreshorten when its size is mismatched with the parent vessel makes its use more difficult for cervical carotid pseudoaneurysms, as the parent vessel regains its luminal diameter during the healing phase, and because of its mobility during head movement. We present a novel technique of using a Solitaire detachable stent (ev3 Neurovascular) to anchor PED constructs to mitigate these shortcomings. Two patients with shallow and broad-necked cervical carotid pseudoaneurysms with underlying parent vessel stenosis deemed poor candidates for conventional stent-supported coiling were treated using tandem overlapping PED centered over the neck of the pseudoaneurysm and a Solitaire concentric anchor was deployed to overlap distally and proximally. As predicted, both patients revealed carotid luminal gain after aneurysm thrombosis with attendant migration (3.8 and 2.8mm) and expansion of the PED construct (14% and 7.8%) which remained constrained within the Solitaire anchoring device with persistent luminal patency and no evidence of endoleak at follow-up (3 and 5 months). The use of a concentric anchoring stent can mitigate the inherent tendency of the braided flow-diverting PED to migrate and foreshorten as the target vessel heals upon pseudoaneurysm thrombosis. This novel technique opens the possibility of using PED to treat shallow or fusiform lesions in mobile cervical arteries previously relegated to stent-supported coiling or surgical reconstruction.
血流导向装置(PED;ev3 Neurovascular,尔湾,加利福尼亚州,美国)为颅内宽颈和梭形动脉瘤提供了已被证实的血流改道效果。当 PED 的尺寸与母血管不匹配时,PED 往往会发生迁移和缩短,这使得其在颈内动脉假性动脉瘤的治疗中更加困难,因为在愈合阶段母血管会恢复其管腔直径,并且由于其在头部运动期间的移动性。我们提出了一种使用 Solitaire 可解脱支架(ev3 Neurovascular)将 PED 结构锚定以减轻这些缺点的新技术。两名患有浅颈和宽颈颈动脉假性动脉瘤且伴有潜在母血管狭窄的患者,被认为是传统支架辅助弹簧圈治疗的不佳候选者,他们接受了颈内动脉假性动脉瘤颈部的串联重叠 PED 治疗,以及部署了 Solitaire 同心锚定装置以重叠远端和近端。正如预测的那样,两名患者在动脉瘤血栓形成后均显示出颈动脉管腔增大,伴有迁移(3.8 和 2.8mm)和 PED 结构扩张(14%和 7.8%),这些变化仍然被 Solitaire 锚定装置限制,管腔保持通畅,没有证据表明在随访(3 个月和 5 个月)时存在内漏。使用同心锚定支架可以减轻编织血流导向 PED 的固有迁移和缩短趋势,因为在假性动脉瘤血栓形成后,靶血管会愈合。这种新技术为使用 PED 治疗以前被归类为支架辅助弹簧圈治疗或手术重建的移动性颈内动脉的浅或梭形病变开辟了可能性。