Flexer S M, Durham-Hall A C, Steward M A, Robinson J M
Department of Surgery, Bradford Teaching Hospitals NHS Foundation Trust, West Yorkshire, UK,
Surg Endosc. 2014 Jun;28(6):1874-8. doi: 10.1007/s00464-013-3407-4. Epub 2014 Jan 11.
Transanal endoscopic microsurgery (TEMS) is becoming more widespread due to the increasing body of evidence to support its role. Previous published data has reported recurrence rates in excess of 10% for benign polyps after TEMS.
Bradford Royal Infirmary is a tertiary referral centre for TEMS and early rectal cancer in the UK. Data for all TEMS operations were entered into a prospective database over a 7-year period. Demographic data, complications and recurrence rates were recorded. Both benign adenomas and malignant lesions were included.
A total of 164 patients (65% male), with a mean age of 68 years were included; 114 (70%) of the lesions resected were benign adenomas, and 50 (30%) were malignant lesions. Median polyp size was 4 (range 0.6-14.5) cm. Mean length of operation was 55 (range 10-120) min. There were no recurrences in any patients with a benign adenoma resected; two patients with malignant lesions developed recurrences. Three intra-operative complications were recorded, two rectal perforations (repaired primarily, one requiring defunctioning stoma), and a further patient suffered a blood loss of >300 ml requiring transfusion. Six patients developed strictures requiring dilation either endoscopically or under anaesthetic in the post-operative period.
We have demonstrated that TEMS procedures performed in a specialist centre provide low rates of both recurrence and complication. Within a specialist centre, TEMS surgery should be offered to all patients for rectal lesions, both benign and malignant, that are amenable to TEMS.
经肛门内镜显微手术(TEMS)因越来越多的证据支持其作用而日益普及。此前发表的数据报告称,TEMS术后良性息肉的复发率超过10%。
布拉德福德皇家医院是英国TEMS和早期直肠癌的三级转诊中心。在7年期间,将所有TEMS手术的数据录入前瞻性数据库。记录人口统计学数据、并发症和复发率。纳入良性腺瘤和恶性病变。
共纳入164例患者(65%为男性),平均年龄68岁;切除的病变中,114例(70%)为良性腺瘤,50例(30%)为恶性病变。息肉中位大小为4(范围0.6 - 14.5)cm。平均手术时长为55(范围10 - 120)分钟。切除良性腺瘤的患者均无复发;2例恶性病变患者出现复发。记录到3例术中并发症,2例直肠穿孔(均一期修复,1例需要造瘘),另有1例患者失血>300 ml需要输血。6例患者术后出现狭窄,需要在内镜下或麻醉下进行扩张。
我们已经证明,在专科中心进行的TEMS手术复发率和并发症发生率都很低。在专科中心,对于所有适合TEMS的直肠良性和恶性病变患者,都应提供TEMS手术。