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[蛙骨骼肌膜中存在钙依赖性钾通透性的两种成分]

[Two components of calcium-dependent potassium permeability coexist in the membrane of frog skeletal muscle].

作者信息

Traoré F, Cognard C, Potreau D, Raymond G

出版信息

C R Acad Sci III. 1987;305(3):69-72.

PMID:2441824
Abstract

Two components of Ca-dependent K permeabilities were demonstrated in the membrane of voltage-clamped muscles fibres by raising the internal calcium concentration with 3 mM caffeine or 0.1 microM Bay K 8644. One, which is TEA-sensitive, is enhanced by an increase of intracellular calcium and the other, which is apamin-sensitive, is inhibited by high levels of internal calcium concentration.

摘要

通过用3 mM咖啡因或0.1 microM Bay K 8644提高细胞内钙浓度,在电压钳制的肌纤维膜中证实了钙依赖性钾通透性的两个组成部分。一个对TEA敏感,随着细胞内钙增加而增强;另一个对蜂毒明肽敏感,被高水平的细胞内钙浓度所抑制。

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