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[血小板计数为10,000/μL的免疫性血小板减少症合并肾细胞癌的腹腔镜下左半肾切除术]

[Laparoscopic left partial nephrectomy for renal cell carcinoma associated with ITP with platelet count of 10,000/μL].

作者信息

Kubota Yasuaki, Horie Kengo, Nagai Shingo, Maeda Shinichi, Ogawa Mika

机构信息

The department of Urology, Toyota Memorial Hospital.

The department of Hematology, Toyota Memorial Hospital.

出版信息

Hinyokika Kiyo. 2013 Dec;59(12):785-9.

Abstract

A 58-year-old man from Brazil was followed as an outpatient with asymptomatic macroglobulinemia and idiopathic thrombocytopenic purpura (ITP). Abdominal enhanced computed tomographic (CT) scan for elevated liver enzymes revealed a left renal tumor. The tumor was in the middle outer left kidney, measured 18 mm in diameter, was discovered in its early phase, and appeared half exophytic. After investigations, the patient was diagnosed with left renal cell carcinoma associated with ITP. His preoperative platelet count was 10,000/μl ; five days of intravenous gamma globulin therapy with high-dose dexamethasone increased the platelet count to 76,000/μl just before operation. Laparoscopic left partial nephrectomy was performed successfully using the retroperitoneal approach. The renal artery was clamped and the tumor excised with an adequate margin. Renal parenchymal repair was completed using running sutures. Ischemia time was 16 minutes. There was no severe oozing of blood intraoperatively. The platelet count decreased to 15,000/μl on postoperative day three (POD 3), and there was oozing of blood around the retroperitoneal drain tube. The bleeding stopped after administration of platelet transfusion. The patient was discharged on POD 9. The histopathological diagnosis was clear cell carcinoma, and surgical margins were negative.

摘要

一名来自巴西的58岁男性作为门诊患者接受无症状巨球蛋白血症和特发性血小板减少性紫癜(ITP)的随访。因肝酶升高进行腹部增强计算机断层扫描(CT)时发现左肾肿瘤。肿瘤位于左肾中外侧,直径18毫米,处于早期阶段,呈半外生性。经过检查,患者被诊断为与ITP相关的左肾细胞癌。其术前血小板计数为10,000/μl;术前五天静脉注射大剂量地塞米松并联合静脉注射丙种球蛋白治疗,使血小板计数在手术前升至76,000/μl。采用后腹腔镜入路成功实施了腹腔镜左肾部分切除术。夹闭肾动脉并完整切除肿瘤,切缘足够。用连续缝合完成肾实质修复。缺血时间为16分钟。术中无严重渗血。术后第3天(POD 3)血小板计数降至15,000/μl,腹膜后引流管周围有渗血。输注血小板后出血停止。患者于POD 9出院。组织病理学诊断为透明细胞癌,手术切缘阴性。

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