Bioengineering Unit, University of Strathclyde, Glasgow, UK Scottish Centre for Innovation in Spinal Cord Injury (SCISCI), Queen Elizabeth National Spinal Injuries Unit, Southern General Hospital, Glasgow, UK Physical Therapy Program, Eugene Applebaum College of Pharmacy and Health Care Sciences, Wayne State University, Detroit, MI, USA.
Bioengineering Unit, University of Strathclyde, Glasgow, UK Scottish Centre for Innovation in Spinal Cord Injury (SCISCI), Queen Elizabeth National Spinal Injuries Unit, Southern General Hospital, Glasgow, UK.
NeuroRehabilitation. 2014;34(2):287-95. doi: 10.3233/NRE-131042.
Strength changes in lower limb muscles following robot assisted gait training (RAGT) in subjects with incomplete spinal cord injury (ISCI) has not been quantified using objective outcome measures.
To record changes in the force generating capacity of lower limb muscles (recorded as peak voluntary isometric torque at the knee and hip), before, during and after RAGT in both acute and subacute/chronic ISCI subjects using a repeated measures study design.
Eighteen subjects with ISCI participated in this study (Age range: 26-63 years mean age = 49.3 ± 11 years). Each subject participated in the study for a total period of eight weeks, including 6 weeks of RAGT using the Lokomat system (Hocoma AG, Switzerland). Peak torques were recorded in hip flexors, extensors, knee flexors and extensors using torque sensors that are incorporated within the Lokomat.
All the tested lower limb muscle groups showed statistically significant (p < 0.001) increases in peak torques in the acute subjects. Comparison between the change in peak torque generated by a muscle and its motor score over time showed a non-linear relationship.
The peak torque recorded during isometric contractions provided an objective outcome measure to record changes in muscle strength following RAGT.
使用客观的结果测量方法,尚未对不完全性脊髓损伤(ISCI)患者在接受机器人辅助步态训练(RAGT)后下肢肌肉力量的变化进行量化。
使用重复测量研究设计,在急性和亚急性/慢性 ISCI 患者中,记录 RAGT 前后下肢肌肉(记录为膝关节和髋关节的峰值自主等长扭矩)产生能力的变化。
18 名 ISCI 患者参加了这项研究(年龄范围:26-63 岁,平均年龄= 49.3±11 岁)。每位患者总共参加了 8 周的研究,其中包括 6 周使用 Lokomat 系统(Hocoma AG,瑞士)进行的 RAGT。使用内置在 Lokomat 中的扭矩传感器记录髋关节屈肌、伸肌、膝关节屈肌和伸肌的峰值扭矩。
所有测试的下肢肌肉群在急性患者中均表现出统计学上显著(p<0.001)的峰值扭矩增加。比较肌肉产生的峰值扭矩变化与其运动评分随时间的关系显示出非线性关系。
等长收缩期间记录的峰值扭矩提供了一种客观的结果测量方法,可记录 RAGT 后肌肉力量的变化。