Li Haoquan, Spannenberg Anke, Neumann Helfried, Beller Matthias, Wu Xiao-Feng
Leibniz-Institut für Katalyse e.V., Albert Einstein Straße, 29a, 18059 Rostock, Germany.
Chem Commun (Camb). 2014 Feb 28;50(17):2114-6. doi: 10.1039/c3cc48490d. Epub 2014 Jan 13.
A highly regioselective cascade synthesis of 2,3-dihydrobenzodioxepinone from 2-bromophenols and epoxides has been developed. The reactions go through nucleophilic ring-opening of epoxides and subsequent palladium-catalyzed intramolecular alkoxylcarbonylation.
已开发出一种从2-溴苯酚和环氧化物高效区域选择性级联合成2,3-二氢苯并二氧杂环庚酮的方法。该反应通过环氧化物的亲核开环以及随后钯催化的分子内烷氧基羰基化反应进行。