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影像学在小肾肿块的主动监测中的作用。

The role of imaging in the active surveillance of small renal masses.

机构信息

Department of Urology, Academic Medical Center, PO Box 22660, 1100 DD, Amsterdam, The Netherlands.

出版信息

Curr Urol Rep. 2014 Mar;15(3):386. doi: 10.1007/s11934-013-0386-x.

DOI:10.1007/s11934-013-0386-x
PMID:24419971
Abstract

Up to 66 % of renal cell carcinomas are detected as small renal masses before the presence of clinical symptoms. Small renal mass treatment has evolved from the exclusive use of radical nephrectomy to the use of nephron sparing procedures where possible. An increase in elderly and comorbid patients, together with the notion that just 20 % of small renal masses show high malignant potential, has prompted interest in active surveillance as a treatment option. Modern imaging techniques provide objective follow-up parameters, namely size, invasion of collecting system or perirenal fat and enhancement patterns, with minimal complication risks or patient discomfort. This review evaluates recent developments in the field of active surveillance for small renal masses. Special focus is placed on the role of imaging in the primary decision making and subsequent follow-up during active surveillance.

摘要

多达 66%的肾细胞癌在出现临床症状之前被检测为小的肾肿瘤。小的肾肿瘤的治疗已经从单纯的根治性肾切除术发展到尽可能使用保留肾单位的手术。老年和合并症患者的增加,以及只有 20%的小肾肿瘤显示出高恶性潜能的观念,促使人们对主动监测作为一种治疗选择产生了兴趣。现代成像技术提供了客观的随访参数,即大小、集合系统或肾周脂肪的侵犯以及增强模式,其并发症风险或患者不适最小。本综述评估了小的肾肿瘤主动监测领域的最新进展。特别关注的是影像学在主动监测的初始决策和后续随访中的作用。

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本文引用的文献

1
Charlson score as a single pertinent criterion to select candidates for active surveillance among patients with small renal masses.查尔森评分作为在小肾肿块患者中选择主动监测候选者的单一相关标准。
World J Urol. 2014 Apr;32(2):513-8. doi: 10.1007/s00345-013-1131-2. Epub 2013 Jul 20.
2
Clear cell renal cell carcinoma and papillary renal cell carcinoma: differentiation of distinct histological types with multiphase CT.透明细胞肾细胞癌和乳头状肾细胞癌:多期 CT 对不同组织学类型的鉴别。
Diagn Interv Radiol. 2013 Sep-Oct;19(5):387-92. doi: 10.5152/dir.2013.13068.
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Renal mass size: concordance between pathology and radiology.
Evaluation and Management of the Geriatric Urologic Oncology Patient.
老年泌尿肿瘤患者的评估与管理
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肾脏肿块大小:病理与放射学的一致性。
Curr Opin Urol. 2013 Sep;23(5):389-93. doi: 10.1097/MOU.0b013e328363212b.
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AJR Am J Roentgenol. 2013 May;200(5):1054-9. doi: 10.2214/AJR.12.9300.
7
Multiphasic enhancement patterns of small renal masses (≤4 cm) on preoperative computed tomography: utility for distinguishing subtypes of renal cell carcinoma, angiomyolipoma, and oncocytoma.术前 CT 多期增强扫描对≤4cm 小肾脏肿块的强化模式:有助于鉴别肾细胞癌、血管平滑肌脂肪瘤和嗜酸细胞瘤的亚型。
Urology. 2013 Jun;81(6):1265-71. doi: 10.1016/j.urology.2012.12.049. Epub 2013 Apr 17.
8
Real-time elastography for distinguishing angiomyolipoma from renal cell carcinoma: preliminary observations.实时弹性成像在鉴别血管平滑肌脂肪瘤与肾细胞癌中的初步观察。
AJR Am J Roentgenol. 2013 Apr;200(4):W369-75. doi: 10.2214/AJR.12.9139.
9
Distinguishing enhancing from nonenhancing renal masses with dual-source dual-energy CT: iodine quantification versus standard enhancement measurements.用双源双能 CT 鉴别强化和非强化性肾肿块:碘定量与标准强化测量的比较。
Eur Radiol. 2013 Aug;23(8):2288-95. doi: 10.1007/s00330-013-2811-4. Epub 2013 Mar 12.
10
Small solid renal masses: characterization by diffusion-weighted MRI at 3 T.小的肾脏实性肿块:3.0T 磁共振弥散加权成像的特征。
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