糖尿病患者唾液葡萄糖水平与血糖水平的相关性
Correlation of salivary glucose level with blood glucose level in diabetes mellitus.
作者信息
Panchbhai Arati S
机构信息
Department of Oral Medicine and Radiology, Sharad Pawar Dental College and Hospital, DMIMS University Sawangi-Meghe, Wardha India.
出版信息
J Oral Maxillofac Res. 2012 Oct 1;3(3):e3. doi: 10.5037/jomr.2012.3303. eCollection 2012.
OBJECTIVES
There is alarming rise in number of people with diabetes mellitus over these years. If glucose in saliva is linked to glucose in blood it can be used to detect diabetes mellitus at an early stage. The present study is undertaken with the aim to assess the correlation of salivary glucose level with blood glucose level in people with diabetes mellitus.
MATERIAL AND METHODS
For investigations, 2 sets of samples of people with diabetes and the age and sex matched non-diabetic subjects were recruited. The salivary glucose was analyzed in unstimulated whole saliva samples using glucose oxidase method. Pearson's correlation coefficient test was applied to assess the correlation between salivary glucose level and blood glucose level.
RESULTS
The significant (P < 0.05) positive correlation of salivary glucose level and fasting blood glucose level was observed in people with uncontrolled diabetes in both the sets of samples.
CONCLUSIONS
Although study suggests some potential for saliva as a marker in monitoring of diabetes mellitus, there are many aspects that need clarification before we reach to a conclusion.
目的
近年来糖尿病患者人数急剧上升。如果唾液中的葡萄糖与血液中的葡萄糖相关联，那么它可用于早期检测糖尿病。本研究旨在评估糖尿病患者唾液葡萄糖水平与血糖水平之间的相关性。
材料与方法
为进行调查，招募了两组糖尿病患者样本以及年龄和性别匹配的非糖尿病受试者样本。使用葡萄糖氧化酶法对未刺激的全唾液样本中的唾液葡萄糖进行分析。应用Pearson相关系数检验来评估唾液葡萄糖水平与血糖水平之间的相关性。
结果
在两组样本中，未控制的糖尿病患者唾液葡萄糖水平与空腹血糖水平呈显著（P < 0.05）正相关。
结论
尽管研究表明唾液作为糖尿病监测标志物具有一定潜力，但在得出结论之前，还有许多方面需要进一步阐明。
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