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[虫草真菌抗血栓作用的研究现状与展望]

[Current studies and prospect of anti-thrombotic effect of Cordyceps fungi].

作者信息

Li Xiao-Gang, Xiao Jian-Hui

机构信息

Key Laboratory of Cell Engineering of Guizhou Province, Affiliated Hospital of Zunyi Medical College, Zunyi 563000, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2013 Oct;38(19):3246-50.

Abstract

Cordyceps is an entomogenous fungi developed after being infected by insects or arthropods. Many varieties of entomogenous fungus show a huge application prospect in functional food and biological medicine fields. Among them, famous herb C. sinensis is their most excellent representative, and mainly used to replenish kidneys and moisten lungs, treating fatigue, night sweating, cardiovascular diseases, respiratory diseases, hypertension, hyperlipidemia, hyperglycemia, renal failure and so on. Currently, as a medicinal resource, C. sinensis has aroused attention from the world. In the past 20 years, many studies found that Cordyceps fungi show the anti-thrombotic effect, as well as a good potential for becoming a patent medicine. This article summarizes studies on Cordyceps fungi's effects in reducing blood viscosity and resisting platelet aggregation and anticoagulant, so as to provide thought for developing and utilizing these resources as anti-thrombotic medicines.

摘要

冬虫夏草是一种被昆虫或节肢动物感染后形成的虫生真菌。许多种类的虫生真菌在功能食品和生物医药领域展现出巨大的应用前景。其中,著名的中药材冬虫夏草就是它们最杰出的代表,主要用于补肾润肺,治疗疲劳、盗汗、心血管疾病、呼吸系统疾病、高血压、高血脂、高血糖、肾衰竭等。目前,冬虫夏草作为一种药用资源已引起全世界的关注。在过去20年里,许多研究发现虫草真菌具有抗血栓作用,并且具有成为专利药物的良好潜力。本文综述了虫草真菌在降低血液粘度、抗血小板聚集及抗凝方面的作用研究,以期为开发利用这些资源作为抗血栓药物提供思路。

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